Featured Nobel Articles

Elizabeth Blackburn, a member of the Editorial Board of Aging, won the Nobel Prize in Physiology or Medicine 2009, while being a member of the board. Elizabeth Blackburn co-authored a paper published in the first (inaugural) issue of Aging.
Andrew V. Schally, Nobel Prize Laureate, published his paper in Aging.
Shinya Yamanaka won the Nobel Prize in Physiology and Medicine 2012. Shinya Yamanaka co-authored a paper published in Aging.

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Volume 4, Issue 7

July 2012
pp 448—520

Explore This Issue

Editorial Comment

Why is DNA methylation of Igf2 CpG island shore affected during ageing?

Paola Caiafa, Michele Zampieri,

https://doi.org/10.18632/aging.100473 pp 448—449

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Research Perspective

Tumor suppression by p53 without apoptosis and senescence: conundrum or rapalog-like gerosuppression?

Mikhail V. Blagosklonny,

https://doi.org/10.18632/aging.100475 pp 450—455

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Research Papers

An autoregulatory loop reverts the mechanosensitive Sirt1 induction by EGR1 in skeletal muscle cells

Patricia S. Pardo, Aladin M. Boriek,

https://doi.org/10.18632/aging.100470 pp 456—461

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Methylation by Set9 modulates FoxO3 stability and transcriptional activity

Daniel R. Calnan, Ashley E. Webb, Jamie L. White, Timothy R. Stowe, Tapasree Goswami, Xiaobing Shi, Alexsandra Espejo, Mark T. Bedford, Or Gozani, Steven P. Gygi, Anne Brunet,

https://doi.org/10.18632/aging.100471 pp 462—479

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Metabolomic fingerprint reveals that metformin impairs one-carbon metabolism in a manner similar to the antifolate class of chemotherapy drugs

Bruna Corominas-Faja, Rosa Quirantes-Piné, Cristina Oliveras-Ferraros, Alejandro Vazquez-Martin, Sílvia Cufí, Begoña Martin-Castillo, Vicente Micol, Jorge Joven, Antonio Segura-Carretero, Javier A. Menendez,

https://doi.org/10.18632/aging.100472 pp 480—498

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The lifespan extension effects of resveratrol are conserved in the honey bee and may be driven by a mechanism related to caloric restriction

Brenda Rascón, Basil P. Hubbard, David A. Sinclair, Gro V. Amdam,

pp 499—508

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Space/Population and Time/Age in DNA methylation variability in humans: a study on IGF2/H19 locus in different Italian populations and in mono- and di-zygotic twins of different age

Chiara Pirazzini, Cristina Giuliani, Maria Giulia Bacalini, Alessio Boattini, Miriam Capri, Elisa Fontanesi, Elena Marasco, Vilma Mantovani, Michela Pierini, Elisa Pini, Donata Luiselli, Claudio Franceschi, Paolo Garagnani,

https://doi.org/10.18632/aging.100476 pp 509—520

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