Research Paper Volume 6, Issue 10 pp 856—872

Proteome-wide analysis reveals an age-associated cellular phenotype of in situ aged human fibroblasts

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Figure 1. Abundance ranges of quantified proteins.

For each age group (young, middle aged and old) the quantified proteins were ranked into four classes based on their abundance (log10 of protein intensities). Abundances of quantified proteins spanned approximately five orders of magnitude (right). For each abundance class and age group an enrichment analysis of biological processes was applied. The five most significant biological processes are indicated in the figure.