Research Paper Volume 6, Issue 10 pp 856—872

Proteome-wide analysis reveals an age-associated cellular phenotype of in situ aged human fibroblasts

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Figure 2. Coverage and correlation of mRNA and protein data.

(A) For each age group the quantified transcripts and proteins were compared. Almost all quantified proteins were also present at the mRNA level. (B) Correlation analysis of mRNA and protein abundances for each individual. The mRNA/protein pairs were drawn as hexagons whereby accumulations of pairs are indicated in different colors. Correlation analysis revealed a correlation of about 28% on average between proteins and mRNAs.