Liver-specific deletion of <i>Ppp2cα</i> enhances glucose metabolism and insulin sensitivity

Li Xian; Siyuan Hou; Zan Huang; An Tang; Peiliang Shi; Qinghua Wang; Anying Song; Shujun Jiang; Zhaoyu Lin; Shiying Guo; Xiang Gao

doi:doi:http://dx.doi.org/10.18632/aging.100725

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Research Paper Volume 7, Issue 4 pp 223—232

Liver-specific deletion of Ppp2cα enhances glucose metabolism and insulin sensitivity

Figure 3.

Loss of Ppp2cα significantly alters metabolism. (a) Accumulation of glycogen was detected by PAS staining and (b) decrease of lipid droplets was detected by Oil Red staining (c) Hepatic glycogen content measured in liver and (d) Hepatic TG content of the liver of 10-week-old Ppp2cα^loxp/loxp: Alb and littermate controls following fasting overnight or random fed. Data were analyzed using two-tailed Student's t test (*p < 0.05)