Research Paper Volume 7, Issue 4 pp 233—240
Caloric restriction induces heat shock response and inhibits B16F10 cell tumorigenesis both in vitro and in vivo
Figure 4. Gene expression profiling in response to caloric restriction.
(A) Venn diagram showing the overlap of gene transcripts with significant change in expression in the CR versus AL pairwise comparisons by both B16F10 melanoma cells growing in culture (in vitro) and as tumor xenografts (in vivo). (B) Effect of CR on the expression of a select group of transcripts. (C) Venn diagram showing the overlap of gene sets with significant change in expression in the CR versus AL pairwise comparisons.