Research Paper Volume 8, Issue 12 pp 3375—3389
Impaired energy metabolism of senescent muscle satellite cells is associated with oxidative modifications of glycolytic enzymes
Figure 6. Senescent satellite cells exhibit altered lipid metabolism. (A) Free fatty acids profiling in young (MY) and senescent myoblasts (MS). (B) Increased glycerolipids turnover in senescent cells. PL: phospholipids; TAG: triacylglycerols; DAG: diacylglycerols; MAG: monoacylglycerols; FA: fatty acids; GP: glycerol phosphate. C: choline; E: ethanolamine. (C) Free carnitine and acylcarnitine profiling. The acyl chain length (c) is denoted by the corresponding metabolite number (e.g., C0 = free carnitine, C2 = acetylcarnitine; C3 =proprionylcarnitine). (D) Sphingolipids metabolism in young and senescent myoblasts. Data are expressed as mean ± S.E.M of six independent experiments. * p <0.05. For details of box plots see Figure legend 4.