Featured Nobel Articles

Elizabeth Blackburn, a member of the Editorial Board of Aging, won the Nobel Prize in Physiology or Medicine 2009, while being a member of the board. Elizabeth Blackburn co-authored a paper published in the first (inaugural) issue of Aging.
Andrew V. Schally, Nobel Prize Laureate, published his paper in Aging.
Shinya Yamanaka won the Nobel Prize in Physiology and Medicine 2012. Shinya Yamanaka co-authored a paper published in Aging.

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Volume 8, Issue 12

December 2016
pp 3151—3567

About the Cover

The cover for issue 12 of Aging features Figure 2B, ''Nematodes exposed to RNAi targeting human muscle-aggregate orthologs have fewer and smaller protein aggregates" from Ayyadevara et al.

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Editorials

Nuclear functions of β2-Spectrin in genomic stability

Kalpana Mujoo, Clayton R. Hunt, Tej K Pandita,

https://doi.org/10.18632/aging.101147 pp 3151—3152

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Nrf2: not “lost in translation”

Robert G. Hawley, Irene Riz,

https://doi.org/10.18632/aging.101152 pp 3153—3154

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MUC1-C drives DNA methylation in cancer

Hasan Rajabi, Ashujit Tagde, Donald Kufe,

https://doi.org/10.18632/aging.101153 pp 3155—3156

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Defining ‘good health’

Susan E. Erdman,

https://doi.org/10.18632/aging.101154 pp 3157—3158

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Commentary

Senescence associated macrophages and “macroph-aging”: are they pieces of the same puzzle?

Francesco Prattichizzo, Massimiliano Bonafè, Fabiola Olivieri, Claudio Franceschi,

https://doi.org/10.18632/aging.101133 pp 3159—3160

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Reviews

Proteomic profiling of mitochondria: what does it tell us about the ageing brain?

Thomas Ingram, Lisa Chakrabarti,

https://doi.org/10.18632/aging.101131 pp 3161—3179

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Effect of the micronutrient iodine in thyroid carcinoma angiogenesis

Kayla Daniell, Carmelo Nucera,

https://doi.org/10.18632/aging.101143 pp 3180—3184

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Research Papers

Human exceptional longevity: transcriptome from centenarians is distinct from septuagenarians and reveals a role of Bcl-xL in successful aging

Consuelo Borras, Kheira M. Abdelaziz, Juan Gambini, Eva Serna, Marta Inglés, Monica de la Fuente, Idoia Garcia, Ander Matheu, Paula Sanchís, Angel Belenguer, Alessandra Errigo, Juan- Antonio Avellana, Ana Barettino, Carla Lloret-Fernández, Nuria Flames, Gianni Pes, Leocadio Rodriguez-Mañas, Jose Viña,

https://doi.org/10.18632/aging.101078 pp 3185—3208

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Birth mass is the key to understanding the negative correlation between lifespan and body size in dogs

Rong Fan, Gayla Olbricht, Xavior Baker, Chen Hou,

https://doi.org/10.18632/aging.101081 pp 3209—3222

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Identification of Salvia haenkei as gerosuppressant agent by using an integrated senescence-screening assay

Ivana Matic, Ajinkya Revandkar, Jingjing Chen, Angela Bisio, Stefano Dall’Acqua, Veronica Cocetta, Paola Brun, Giorgio Mancino, Martina Milanese, Maurizio Mattei, Monica Montopoli, Andrea Alimonti,

https://doi.org/10.18632/aging.101076 pp 3223—3240

View Abstract PDF Full-Text How to Cite Special Collection on Cell Senescence and Rapamycin

Serum protein mediators of dementia and aging proper

Donald R. Royall, Safa Al-Rubaye, Ram Bishnoi, Raymond F. Palmer,

https://doi.org/10.18632/aging.101091 pp 3241—3254

View Abstract PDF Full-Text How to Cite Special Collection on Alzheimer's

Slm35 links mitochondrial stress response and longevity through TOR signaling pathway

Jose L. Aguilar-Lopez, Raymond Laboy, Fabiola Jaimes-Miranda, Erika Garay, Alexander DeLuna, Soledad Funes,

https://doi.org/10.18632/aging.101093 pp 3255—3271

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Age-related changes in the gene expression profile of antigen-specific mouse CD8+ T cells can be partially reversed by blockade of the BTLA/CD160 pathways during vaccination

Noor Dawany, Elizabeth M Parzych, Louise C Showe, Hildegund CJ Ertl,

https://doi.org/10.18632/aging.101105 pp 3272—3297

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miR-34a is a common link in both HIV- and antiretroviral therapy-induced vascular aging

Jiaxin Zhan, Shanshan Qin, Lili Lu, Xiamin Hu, Jun Zhou, Yeying Sun, Jian Yang, Ying Liu, Zunzhe Wang, Ning Tan, Jiyan Chen, Chunxiang Zhang,

https://doi.org/10.18632/aging.101118 pp 3298—3310

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Association between genetic variants in the XPG gene and gastric cancer risk in a Southern Chinese population

Rui-Xi Hua, Zhen-Jian Zhuo, Jinhong Zhu, Dan-Hua Jiang, Wen-Qiong Xue, Shao-Dan Zhang, Jiang-Bo Zhang, Xi-Zhao Li, Pei-Fen Zhang, Wei-Hua Jia, Guo-Ping Shen, Jing He,

https://doi.org/10.18632/aging.101119 pp 3311—3320

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RelA NF-κB subunit activation as a therapeutic target in diffuse large B-cell lymphoma

Mingzhi Zhang, Zijun Y. Xu-Monette, Ling Li, Ganiraju C. Manyam, Carlo Visco, Alexandar Tzankov, Jing Wang, Santiago Montes-Moreno, Karen Dybkaer, April Chiu, Attilio Orazi, Youli Zu, Govind Bhagat, Kristy L. Richards, Eric D. Hsi, William W.L. Choi, J. Han van Krieken, Jooryung Huh, Maurilio Ponzoni, Andrés J.M. Ferreri, Michael B. Møller, Ben M. Parsons, Jane N. Winter, Miguel A. Piris, L. Jeffrey Medeiros, Lan V. Pham, Ken H. Young,

https://doi.org/10.18632/aging.101121 pp 3321—3340

View Abstract PDF Full-Text How to Cite Special Collection on Cancer Therapeutics

Effects of dietary restriction on adipose mass and biomarkers of healthy aging in human

Daniele Lettieri-Barbato, Esmeralda Giovannetti, Katia Aquilano,

https://doi.org/10.18632/aging.101122 pp 3341—3355

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Altered stoichiometry and nuclear delocalization of NonO and PSF promote cellular senescence

Ching-Jung Huang, Utsab Das, Weijun Xie, Miryam Ducasse, Haley O. Tucker,

https://doi.org/10.18632/aging.101125 pp 3356—3374

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Impaired energy metabolism of senescent muscle satellite cells is associated with oxidative modifications of glycolytic enzymes

Martín A. Baraibar, Janek Hyzewicz, Adelina Rogowska-Wrzesinska, Anne-Laure Bulteau, Carina Prip-Buus, Gillian Butler-Browne, Bertrand Friguet,

https://doi.org/10.18632/aging.101126 pp 3375—3389

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Aging promotes neoplastic disease through effects on the tissue microenvironment

Fabio Marongiu, Maria Paola Serra, Silvia Doratiotto, Marcella Sini, Maura Fanti, Erika Cadoni, Monica Serra, Ezio Laconi,

https://doi.org/10.18632/aging.101128 pp 3390—3399

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Calcium alterations signal either to senescence or to autophagy induction in stem cells upon oxidative stress

Aleksandra V. Borodkina, Alla N. Shatrova, Pavel I. Deryabin, Anastasiia A. Griukova, Polina A. Abushik, Sergei M. Antonov, Nikolay N. Nikolsky, Elena B. Burova,

https://doi.org/10.18632/aging.101130 pp 3400—3418

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Quiescin-sulfhydryl oxidase inhibits prion formation in vitro

Yi-An Zhan, Romany Abskharon, Yu Li, Jue Yuan, Liang Zeng, Johnny Dang, Manuel Camacho Martinez, Zerui Wang, Jacqueline Mikol, Sylvain Lehmann, Shizhong Bu, Jan Steyaert, Li Cui, Robert B. Petersen, Qingzhong Kong, Gong-Xiang Wang, Alexandre Wohlkonig, Wen-Quan Zou,

https://doi.org/10.18632/aging.101132 pp 3419—3429

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Early and progressive deficit of neuronal activity patterns in a model of local amyloid pathology in mouse prefrontal cortex

Fani Koukouli, Marie Rooy, Uwe Maskos,

https://doi.org/10.18632/aging.101136 pp 3430—3449

View Abstract PDF Full-Text How to Cite Special Collection on Alzheimer's

Altered S-nitrosylation of p53 is responsible for impaired antioxidant response in skeletal muscle during aging

Sara Baldelli, Maria Rosa Ciriolo,

https://doi.org/10.18632/aging.101139 pp 3450—3467

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Naked mole-rats maintain healthy skeletal muscle and Complex IV mitochondrial enzyme function into old age

Elizabeth A Stoll, Nevena Karapavlovic, Hannah Rosa, Michael Woodmass, Karolina Rygiel, Kathryn White, Douglass M Turnbull, Chris G Faulkes,

https://doi.org/10.18632/aging.101140 pp 3468—3485

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Proteins that accumulate with age in human skeletal-muscle aggregates contribute to declines in muscle mass and function in Caenorhabditis elegans

Srinivas Ayyadevara, Meenakshisundaram Balasubramaniam, Pooja Suri, Samuel G. Mackintosh, Alan J. Tackett, Dennis H. Sullivan, Robert J. Shmookler Reis, Richard A. Dennis,

https://doi.org/10.18632/aging.101141 pp 3486—3497

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Accumulation of spontaneous γH2AX foci in long-term cultured mesenchymal stromal cells

Margarita Pustovalova, Anna Grekhova, Тatiana Astrelina, Viktoria Nikitina, Ekaterina Dobrovolskaya, Yulia Suchkova, Irina Kobzeva, Darya Usupzhanova, Natalia Vorobyeva, Aleksandr Samoylov, Andrey Bushmanov, Ivan V. Ozerov, Alex Zhavoronkov, Sergey Leonov, Dmitry Klokov, Andreyan N. Osipov,

https://doi.org/10.18632/aging.101142 pp 3498—3506

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TFEB ameliorates the impairment of the autophagy-lysosome pathway in neurons induced by doxorubicin

Jose Felix Moruno-Manchon, Ndidi-Ese Uzor, Shelli R. Kesler, Jeffrey S. Wefel, Debra M. Townley, Archana Sidalaghatta Nagaraja, Sunila Pradeep, Lingegowda S. Mangala, Anil K. Sood, Andrey S. Tsvetkov,

https://doi.org/10.18632/aging.101144 pp 3507—3519

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Delivery of sFIT-1 engineered MSCs in combination with a continuous low-dose doxorubicin treatment prevents growth of liver cancer

Jian Niu, Yue Wang, Ji Wang, Liu Bin, Xin Hu,

https://doi.org/10.18632/aging.101146 pp 3520—3534

View Abstract PDF Full-Text How to Cite Special Collection on Cancer Therapeutics

Gerosuppression by pan-mTOR inhibitors

Olga V. Leontieva, Mikhail V. Blagosklonny,

https://doi.org/10.18632/aging.101155 pp 3535—3551

View Abstract PDF Full-Text How to Cite Special Collection on Cell Senescence and Rapamycin

Sodium fluoride (NaF) induces the splenic apoptosis via endoplasmic reticulum (ER) stress pathway in vivo and in vitro

Huidan Deng, Ping Kuang, Hengmin Cui, Lian Chen, Qin Luo, Jing Fang, Zhicai Zuo, Junliang Deng, Xun Wang, Ling Zhao,

https://doi.org/10.18632/aging.101150 pp 3552—3567

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Featured Nobel Articles

Volume 8, Issue 12

About the Cover

Editorials

Kalpana Mujoo, Clayton R. Hunt, Tej K Pandita,

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Robert G. Hawley, Irene Riz,

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Hasan Rajabi, Ashujit Tagde, Donald Kufe,

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Susan E. Erdman,

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Commentary

Francesco Prattichizzo, Massimiliano Bonafè, Fabiola Olivieri, Claudio Franceschi,

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Reviews

Thomas Ingram, Lisa Chakrabarti,

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Kayla Daniell, Carmelo Nucera,

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Research Papers

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Rong Fan, Gayla Olbricht, Xavior Baker, Chen Hou,

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Ivana Matic, Ajinkya Revandkar, Jingjing Chen, Angela Bisio, Stefano Dall’Acqua, Veronica Cocetta, Paola Brun, Giorgio Mancino, Martina Milanese, Maurizio Mattei, Monica Montopoli, Andrea Alimonti,

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Donald R. Royall, Safa Al-Rubaye, Ram Bishnoi, Raymond F. Palmer,

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Jose L. Aguilar-Lopez, Raymond Laboy, Fabiola Jaimes-Miranda, Erika Garay, Alexander DeLuna, Soledad Funes,

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Noor Dawany, Elizabeth M Parzych, Louise C Showe, Hildegund CJ Ertl,

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Jiaxin Zhan, Shanshan Qin, Lili Lu, Xiamin Hu, Jun Zhou, Yeying Sun, Jian Yang, Ying Liu, Zunzhe Wang, Ning Tan, Jiyan Chen, Chunxiang Zhang,

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Rui-Xi Hua, Zhen-Jian Zhuo, Jinhong Zhu, Dan-Hua Jiang, Wen-Qiong Xue, Shao-Dan Zhang, Jiang-Bo Zhang, Xi-Zhao Li, Pei-Fen Zhang, Wei-Hua Jia, Guo-Ping Shen, Jing He,

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Daniele Lettieri-Barbato, Esmeralda Giovannetti, Katia Aquilano,

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Ching-Jung Huang, Utsab Das, Weijun Xie, Miryam Ducasse, Haley O. Tucker,

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Martín A. Baraibar, Janek Hyzewicz, Adelina Rogowska-Wrzesinska, Anne-Laure Bulteau, Carina Prip-Buus, Gillian Butler-Browne, Bertrand Friguet,

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