Research Paper Volume 8, Issue 12 pp 3552—3567
Sodium fluoride (NaF) induces the splenic apoptosis via endoplasmic reticulum (ER) stress pathway in vivo and in vitro
Figure 3. Effect of NaF on apoptosis in the spleen at 21 (A, C) and 42 (B, D) days of age. (a-d) Two-dimension scatter plots depicting distribution of cells positively stained for Annexin V-PE/7-AAD. (a) CG, (b) 12 mg/kg group, (c) 24 mg/kg group and (d) 48 mg/kg group. (C-D) Quantitative analysis of total apoptotic lymphocytes. Data are presented with the means ± standard deviation, * p < 0.05, ** p < 0.01, compared with the control group. Data were analyzed by the variance (ANOVA) test of the SPSS 19.0 software.