Research Paper Volume 9, Issue 3 pp 790—802

Effect of intranasally administered insulin on cerebral blood flow and perfusion; a randomized experiment in young and older adults

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Figure 4. Flowchart of experimental procedures related to cerebral blood flow and perfusion measurements. After an overnight fast and baseline measures, the study day started at 08.00 with blood sample withdrawal for baseline measures, after which subjects received either the intranasal insulin or intranasal placebo treatment. MRI scanning began 20 mins later, including survey/structural MRI scans, flow and perfusion scans.