Figure 2. Metformin abrogates rapamycin-mediated glucose intolerance in female mice. Glucose tolerance tests performed in male (left) and female (right) mice following (A) 1, (B) 2, (C) 3, or (D) 9 months of indicated diet treatments. Symbols represent mean values for indicated group at each time point ± SEM. For all groups, n=8-10.