Figure 1. Schematic diagram showing the main points pertaining to the study. Abbreviations: AIS, acute ischemic stroke; CCI, Chronic cerebral ischemia; SAH, subarachnoid hemorrhage; CEA, carotid endarterectomy; CAS, carotid angioplasty and stenting; CSVD, cerebral small vessel disease; TBI, traumatic brain injury; CABG, coronary artery bypass graft surgery; SPCI, selective percutaneous coronary intervention; PPCI, primary percutaneous coronary intervention; CHF, chronic heart failure; ARD, acute renal dysfunction.