Featured Nobel Articles

Elizabeth Blackburn, a member of the Editorial Board of Aging, won the Nobel Prize in Physiology or Medicine 2009, while being a member of the board. Elizabeth Blackburn co-authored a paper published in the first (inaugural) issue of Aging.
Andrew V. Schally, Nobel Prize Laureate, published his paper in Aging.
Shinya Yamanaka won the Nobel Prize in Physiology and Medicine 2012. Shinya Yamanaka co-authored a paper published in Aging.

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Volume 10, Issue 8

August 2018
pp 1789—2211

About the Cover

The cover for issue 8 of Aging features Figure 1 "GRSF1 levels decline with senescence" from Noh et al.

Explore This Issue

Editorials

Aging and brain plasticity

Lisa Pauwels, Sima Chalavi, Stephan P. Swinnen,

https://doi.org/10.18632/aging.101514 pp 1789—1790

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A promising connection between BDNF and Alzheimer’s disease

Maria Laura Giuffrida, Agata Copani, Enrico Rizzarelli,

https://doi.org/10.18632/aging.101518 pp 1791—1792

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Neural stem cell spacing questions their self-renewal

Olga Mineyeva, Alexei Koulakov, Grigori Enikolopov,

https://doi.org/10.18632/aging.101519 pp 1793—1794

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Correction of aging phenotype in the liver

Katherine Rodriguez, Ashley Cast, Nikolai A. Timchenko,

https://doi.org/10.18632/aging.101523 pp 1795—1796

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A brief history of acute stroke care

Rahul Damani,

https://doi.org/10.18632/aging.101542 pp 1797—1798

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News

Epigenetic clocks galore: a new improved clock predicts age-acceleration in Hutchinson Gilford Progeria Syndrome patients

Andrew E. Teschendorff,

https://doi.org/10.18632/aging.101533 pp 1799—1800

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Reviews

Liver regeneration in aged mice: new insights

Monica Pibiri,

https://doi.org/10.18632/aging.101524 pp 1801—1824

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Remote ischemic conditioning: a promising therapeutic intervention for multi-organ protection

Da Zhou, Jiayue Ding, Jingyuan Ya, Liqun Pan, Yuan Wang, Xunming Ji, Ran Meng,

https://doi.org/10.18632/aging.101527 pp 1825—1855

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Priority Research Paper

GRSF1 suppresses cell senescence

Ji Heon Noh, Kyoung Mi Kim, M. Laura Idda, Jennifer L. Martindale, Xiaoling Yang, Kotb Abdelmohsen, Myriam Gorospe,

https://doi.org/10.18632/aging.101516 pp 1856—1866

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Research Papers

Matcha green tea (MGT) inhibits the propagation of cancer stem cells (CSCs), by targeting mitochondrial metabolism, glycolysis and multiple cell signalling pathways

Gloria Bonuccelli, Federica Sotgia, Michael P. Lisanti,

https://doi.org/10.18632/aging.101483 pp 1867—1883

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Anillin is required for tumor growth and regulated by miR-15a/miR-16-1 in HBV-related hepatocellular carcinoma

Yi-Fan Lian, Yan-Lin Huang, Jia-Liang Wang, Mei-Hai Deng, Tian-Liang Xia, Mu-Sheng Zeng, Min-Shan Chen, Hong-Bo Wang, Yue-Hua Huang,

https://doi.org/10.18632/aging.101510 pp 1884—1901

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Aging aggravates hepatic ischemia-reperfusion injury in mice by impairing mitophagy with the involvement of the EIF2α-parkin pathway

Yang Li, Dan-yun Ruan, Chang-chang Jia, Jun Zheng, Guo-ying Wang, Hui Zhao, Qing Yang, Wei Liu, Shu-hong Yi, Hua Li, Gen-shu Wang, Yang Yang, Gui-hua Chen, Qi Zhang,

https://doi.org/10.18632/aging.101511 pp 1902—1920

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Serum CNPY2 isoform 2 represents a novel biomarker for early detection of colorectal cancer

Jianhong Peng, Qingjian Ou, Zhizhong Pan, Rongxin Zhang, Yujie Zhao, Yuxiang Deng, Zhenhai Lu, Lin Zhang, Caixia Li, Yaxian Zhou, Jian Guo, Desen Wan, Yujing Fang,

https://doi.org/10.18632/aging.101512 pp 1921—1931

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Sirt6 deficiency impairs corneal epithelial wound healing

Xiaobing Hu, Shuang Zhu, Rong Liu, Jordan D. Miller, Kevin Merkley, Ronald G. Tilton, Hua Liu,

https://doi.org/10.18632/aging.101513 pp 1932—1946

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Impact of demography and population dynamics on the genetic architecture of human longevity

Cristina Giuliani, Marco Sazzini, Chiara Pirazzini, Maria Giulia Bacalini, Elena Marasco, Guido Alberto Gnecchi Ruscone, Fang Fang, Stefania Sarno, Davide Gentilini, Anna Maria Di Blasio, Paolina Crocco, Giuseppe Passarino, Daniela Mari, Daniela Monti, Benedetta Nacmias, Sandro Sorbi, Carlo Salvarani, Mariagrazia Catanoso, Davide Pettener, Donata Luiselli, Svetlana Ukraintseva, Anatoliy Yashin, Claudio Franceschi, Paolo Garagnani,

https://doi.org/10.18632/aging.101515 pp 1947—1963

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Circ-BPTF promotes bladder cancer progression and recurrence through the miR-31-5p/RAB27A axis

Junming Bi, Hongwei Liu, Zijian Cai, Wei Dong, Ning Jiang, Meihua Yang, Jian Huang, Tianxin Lin,

https://doi.org/10.18632/aging.101520 pp 1964—1976

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Identification of IDH-mutant gliomas by a prognostic signature according to gene expression profiling

Qiangwei Wang, Zhiliang Wang, Guanzhang Li, Chuanbao Zhang, Zhaoshi Bao, Zheng Wang, Gan You, Tao Jiang,

https://doi.org/10.18632/aging.101521 pp 1977—1988

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Relevance of XPD polymorphisms to neuroblastoma risk in Chinese children: a four-center case-control study

Jiwen Cheng, Zhenjian Zhuo, Yijuan Xin, Pu Zhao, Weili Yang, Haixia Zhou, Jiao Zhang, Ya Gao, Jing He, Peng Li,

https://doi.org/10.18632/aging.101522 pp 1989—2000

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MicroRNA-221 silencing attenuates the degenerated phenotype of intervertebral disc cells

Letizia Penolazzi, Elisabetta Lambertini, Leticia Scussel Bergamin, Tosca Roncada, Pasquale De Bonis, Michele Cavallo, Roberta Piva,

https://doi.org/10.18632/aging.101525 pp 2001—2015

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Lycopene ameliorates oxidative stress in the aging chicken ovary via activation of Nrf2/HO-1 pathway

Xingting Liu, Xin Lin, Siyu Zhang, Changquan Guo, Jian Li, Yuling Mi, Caiqiao Zhang,

https://doi.org/10.18632/aging.101526 pp 2016—2036

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The long non-coding RNA FLJ46906 binds to the transcription factors NF-κB and AP-1 and regulates expression of aging-associated genes

Kazuyuki Yo, Thomas M. Rünger,

https://doi.org/10.18632/aging.101528 pp 2037—2050

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Inverse relationship between serum hsCRP concentration and hand grip strength in older adults: a nationwide population-based study

Beom-Jun Kim, Seung Hun Lee, Mi Kyung Kwak, Carlos M. Isales, Jung-Min Koh, Mark W. Hamrick,

https://doi.org/10.18632/aging.101529 pp 2051—2061

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LncRNA BANCR promotes tumorigenesis and enhances adriamycin resistance in colorectal cancer

Siping Ma, Dongxiang Yang, Yanlong Liu, Yongpeng Wang, Tao Lin, Yanxi Li, Shihua Yang, Wanchuan Zhang, Rui Zhang,

https://doi.org/10.18632/aging.101530 pp 2062—2078

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Integrated analysis of the impact of age on genetic and clinical aspects of hepatocellular carcinoma

Manar Atyah, Yi-Rui Yin, Chen-Hao Zhou, Qiang Zhou, Wan-Yong Chen, Qiong-Zhu Dong, Ning Ren,

https://doi.org/10.18632/aging.101531 pp 2079—2097

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Impaired autophagic activity and ATG4B deficiency are associated with increased endoplasmic reticulum stress-induced lung injury

Mariana Maciel, Daniel Hernández-Barrientos, Iliana Herrera, Moisés Selman, Annie Pardo, Sandra Cabrera,

https://doi.org/10.18632/aging.101532 pp 2098—2112

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MiR-146b inhibits autophagy in prostate cancer by targeting the PTEN/Akt/mTOR signaling pathway

Song Gao, Zhiying Zhao, Rong Wu, Lina Wu, Xin Tian, Zhenyong Zhang,

https://doi.org/10.18632/aging.101534 pp 2113—2121

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A Drosophila model of cigarette smoke induced COPD identifies Nrf2 signaling as an expedient target for intervention

Ruben Prange, Marcus Thiedmann, Anita Bhandari, Neha Mishra, Anupam Sinha, Robert Häsler, Philipp Rosenstiel, Karin Uliczka, Christina Wagner, Ali Önder Yildirim, Christine Fink, Thomas Roeder,

https://doi.org/10.18632/aging.101536 pp 2122—2135

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p62 /SQSTM1 coding plasmid prevents age related macular degeneration in a rat model

Nataliya G. Kolosova, Oyuna S. Kozhevnikova, Darya V. Telegina, Anzhela Zh. Fursova, Natalia A. Stefanova, Natalia A. Muraleva, Franco Venanzi, Michael Y. Sherman, Sergey I. Kolesnikov, Albert A. Sufianov, Vladimir L. Gabai, Alexander M. Shneider,

https://doi.org/10.18632/aging.101537 pp 2136—2147

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Gender- and region-specific changes in estrogen signaling in aging rat brain mitochondria

Christopher M. Evola, Tanner L. Hudson, Luping Huang, Adrian M. Corbett, Debra A. Mayes,

https://doi.org/10.18632/aging.101538 pp 2148—2169

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Exposure to Zinc oxide nanoparticles during pregnancy induces oocyte DNA damage and affects ovarian reserve of mouse offspring

Qiu-Yue Zhai, Wei Ge, Jun-Jie Wang, Xiao-Feng Sun, Jin-Mei Ma, Jing-Cai Liu, Yong Zhao, Yan-Zhong Feng, Paul W. Dyce, Massimo De Felici, Wei Shen,

https://doi.org/10.18632/aging.101539 pp 2170—2189

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Qualitative and quantitative alterations in intracellular and membrane glycoproteins maintain the balance between cellular senescence and human aging

Yoko Itakura, Norihiko Sasaki, Masashi Toyoda,

https://doi.org/10.18632/aging.101540 pp 2190—2208

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Letter to the Editor

Spermidine delays aging in humans

Frank Madeo, Didac Carmona-Gutierrez, Oliver Kepp, Guido Kroemer,

https://doi.org/10.18632/aging.101517 pp 2209—2211

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