Research Paper Volume 10, Issue 12 pp 3986—3999

Injury factors alter miRNAs profiles of exosomes derived from islets and circulation

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Figure 4. Validation of exosomal miRNAs detected by microarray. Four miRNAs with top high FC values (FC>1.5 in both STZ and cytokines treated groups) miR-375-3p (A), miR-129-5p (B), miR-378a-3p (C), miR-382-5p (D) were further verified by qRT-PCR in three independent samples. The data are presented as mean±SEM. (* P<0.05, ** P<0.01 compared with control).