Volume 10, Issue 12

THC for age-related cognitive decline?

Yosef Sarne,

https://doi.org/10.18632/aging.101648 pp 3628—3629

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How age affects reinforcement learning

Itamar Lerner, Ravi Sojitra, Mark Gluck,

https://doi.org/10.18632/aging.101649 pp 3630—3631

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Autophagy in neurodegeneration and aging

Yasuo Miki, Janice L Holton, Koichi Wakabayashi,

https://doi.org/10.18632/aging.101652 pp 3632—3633

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Vascular inflammation in aging

Indranil Biwas, Alireza R. Rezaie,

https://doi.org/10.18632/aging.101653 pp 3634—3635

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Gender, GABAergic dysfunction and AD

A. Alia, Steffen Roßner,

https://doi.org/10.18632/aging.101672 pp 3636—3637

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Recycling the LDL receptor to combat atherosclerosis

Dyonne Vos, Jan Albert Kuivenhoven, Bart van de Sluis,

https://doi.org/10.18632/aging.101681 pp 3638—3640

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Role of echocardiography in CRT

Bhupendar Tayal, Peter Sogaard,

https://doi.org/10.18632/aging.101687 pp 3641—3642

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Erythrocytes and cardiovascular complications

Zhichao Zhou, Jiangning Yang, John Pernow,

https://doi.org/10.18632/aging.101688 pp 3643—3644

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Aging, inhibition and GABA

Lisa Pauwels, Celine Maes, Stephan P. Swinnen,

https://doi.org/10.18632/aging.101696 pp 3645—3646

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Molecular insights into vascular aging

Kirsty Foote, Martin R. Bennett,

https://doi.org/10.18632/aging.101697 pp 3647—3649

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Abdominal aortic aneurysm in aged population

Ryoko Umebayashi, Haruhito A. Uchida, Jun Wada,

https://doi.org/10.18632/aging.101702 pp 3650—3651

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Pyrophosphate metabolism and calcification

Magda R. Hamczyk, Ricardo Villa-Bellosta,

https://doi.org/10.18632/aging.101703 pp 3652—3653

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mTOR, glycotoxins and the parallel universe

Alan S. Green,

https://doi.org/10.18632/aging.101720 pp 3654—3656

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Autophagy delays progression of the two most frequent human monogenetic lethal diseases: cystic fibrosis and Wilson disease

Luigi Maiuri, Guido Kroemer,

https://doi.org/10.18632/aging.101736 pp 3657—3661

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Long noncoding RNA B3GALT5-AS1 suppresses colon cancer liver metastasis via repressing microRNA-203

Liang Wang, Zhewei Wei, Kaiming Wu, Weigang Dai, Changhua Zhang, Jianjun Peng, Yulong He,

https://doi.org/10.18632/aging.101628 pp 3662—3682

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A functional variant of SMAD4 enhances macrophage recruitment and inflammatory response via TGF-β signal activation in Thoracic aortic aneurysm and dissection

Ying Wang, Pei Yin, Yi-Huan Chen, Yun-Sheng Yu, Wen-Xue Ye, Hao-Yue Huang, Zhen-Chun Ji, Zhen-Ya Shen,

https://doi.org/10.18632/aging.101662 pp 3683—3701

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BCAR4 activates GLI2 signaling in prostate cancer to contribute to castration resistance

Zhiping Cai, Yapei Wu, Yao Li, Jizhong Ren, Linhui Wang,

https://doi.org/10.18632/aging.101664 pp 3702—3712

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Reduced production of laminin by hepatic stellate cells contributes to impairment in oval cell response to liver injury in aged mice

Liu Qian, Hui Zhang, Yuting Gu, Dechun Li, Songbing He, Hui Wang, Yiji Cheng, Wanlin Yang, Hongshuang Yu, Xiaonan Zhao, Wei Cai, Lijun Meng, Min Jin, Yanan Wang, Yanyun Zhang,

https://doi.org/10.18632/aging.101665 pp 3713—3735

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Inhibition of protein kinase D disrupts spindle formation and actin assembly during porcine oocyte maturation

Yu Zhang, Hong-Hui Wang, Xiang Wan, Yao Xu, Meng-Hao Pan, Shao-Chen Sun,

https://doi.org/10.18632/aging.101667 pp 3736—3744

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TAp73 regulates ATP7A: possible implications for ageing-related diseases

Piervito Lopriore, Nazzareno Capitanio, Emanuele Panatta, Nicola Di Daniele, Alessandra Gambacurta, Gerry Melino, Ivano Amelio,

https://doi.org/10.18632/aging.101669 pp 3745—3760

View Abstract PDF Full-Text How to Cite Special Collection on p53 Part 2

DNA methylation-based age prediction and telomere length in white blood cells and cumulus cells of infertile women with normal or poor response to ovarian stimulation

Scott J. Morin, Xin Tao, Diego Marin, Yiping Zhan, Jessica Landis, Jenna Bedard, Richard T. Scott Jr., Emre Seli,

https://doi.org/10.18632/aging.101670 pp 3761—3773

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A CREB1/miR-433 reciprocal feedback loop modulates proliferation and metastasis in colorectal cancer

Li Yan, Wei-Qiang You, Neng-Quan Sheng, Jian-Feng Gong, Lan-Dian Hu, Ge-Wen Tan, Hong-Qi Chen, Zhi-Gang Wang,

https://doi.org/10.18632/aging.101671 pp 3774—3793

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Sevoflurane impairs learning and memory of the developing brain through post-transcriptional inhibition of CCNA2 via microRNA-19-3p

Xin Zhao, Yanwu Jin, Haibo Li, Yuxiu Jia, Yuelan Wang,

https://doi.org/10.18632/aging.101673 pp 3794—3805

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Circular RNA EIF6 (Hsa_circ_0060060) sponges miR-144-3p to promote the cisplatin-resistance of human thyroid carcinoma cells by autophagy regulation

Feng Liu, Jin Zhang, Long Qin, Ziyao Yang, Jianxia Xiong, Yanyan Zhang, Ruihuan Li, Shujing Li, Huifang Wang, Bo Yu, Wenjun Zhao, Weiran Wang, Zhensu Li, Jing Liu,

https://doi.org/10.18632/aging.101674 pp 3806—3820

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Caloric restriction rescues yeast cells from alpha-synuclein toxicity through autophagic control of proteostasis

Belém Sampaio-Marques, Hélder Pereira, Ana R. Santos, Alexandra Teixeira, Paula Ludovico,

https://doi.org/10.18632/aging.101675 pp 3821—3833

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Tissue iron is negatively correlated with TERC or TERT mRNA expression: a heterochronic parabiosis study in mice

Meng-Wan Zhang, Peng Zhao, Wing-Ho Yung, Yuan Sheng, Ya Ke, Zhong-Ming Qian,

https://doi.org/10.18632/aging.101676 pp 3834—3850

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Aging-dependent decrease in the numbers of enteric neurons, interstitial cells of Cajal and expression of connexin43 in various regions of gastrointestinal tract

Tingyi Sun, Dandan Li, Shilong Hu, Li Huang, Haimei Sun, Shu Yang, Bo Wu, Fengqing Ji, Deshan Zhou,

https://doi.org/10.18632/aging.101677 pp 3851—3865

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Serial position effects differ between Alzheimer’s and vascular features in mild cognitive impairment

Russell Jude Chander, Heidi Foo, Tingting Yong, Levinia Lim, Jayne Tan, Ming-Ching Wen, Adeline Ng, Shahul Hameed, Simon Ting, Juan Zhou, Nagaendran Kandiah,

https://doi.org/10.18632/aging.101678 pp 3866—3880

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Accelerated aging induced by deficiency of Zmpste24 protects old mice to develop bleomycin-induced pulmonary fibrosis

Jazmín Calyeca, Yalbi I. Balderas-Martínez, Raúl Olmos, Rogelio Jasso, Vilma Maldonado, Quetzali Rivera, Moisés Selman, Annie Pardo,

https://doi.org/10.18632/aging.101679 pp 3881—3896

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Melatonin prevents deterioration in quality by preserving epigenetic modifications of porcine oocytes after prolonged culture

Junyu Nie, Peng Xiao, Xuefang Wang, Xiaogan Yang, Huiyan Xu, Kehuan Lu, Shengsheng Lu, Xingwei Liang,

https://doi.org/10.18632/aging.101680 pp 3897—3909

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SIN-3 as a key determinant of lifespan and its sex dependent differential role on healthspan in Caenorhabditis elegans

Renu Pandey, Meenakshi Sharma, Daman Saluja,

https://doi.org/10.18632/aging.101682 pp 3910—3937

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Higher gene expression stability during aging in long-lived giant mole-rats than in short-lived rats

Arne Sahm, Martin Bens, Yoshiyuki Henning, Christiane Vole, Marco Groth, Matthias Schwab, Steve Hoffmann, Matthias Platzer, Karol Szafranski, Philip Dammann,

https://doi.org/10.18632/aging.101683 pp 3938—3956

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Integrated multi-omics characterization reveals a distinctive metabolic signature and the role of NDUFA4L2 in promoting angiogenesis, chemoresistance, and mitochondrial dysfunction in clear cell renal cell carcinoma

Giuseppe Lucarelli, Monica Rutigliano, Fabio Sallustio, Domenico Ribatti, Andrea Giglio, Martina Lepore Signorile, Valentina Grossi, Paola Sanese, Anna Napoli, Eugenio Maiorano, Cristina Bianchi, Roberto A. Perego, Matteo Ferro, Elena Ranieri, Grazia Serino, Lauren N. Bell, Pasquale Ditonno, Cristiano Simone, Michele Battaglia,

https://doi.org/10.18632/aging.101685 pp 3957—3985

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Injury factors alter miRNAs profiles of exosomes derived from islets and circulation

Qi Fu, Hemin Jiang, Zibin Wang, Xingyun Wang, Heng Chen, Ziyang Shen, Lei Xiao, Xirong Guo, Tao Yang,

https://doi.org/10.18632/aging.101689 pp 3986—3999

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The ER-alpha mutation Y537S confers Tamoxifen-resistance via enhanced mitochondrial metabolism, glycolysis and Rho-GDI/PTEN signaling: Implicating TIGAR in somatic resistance to endocrine therapy

Marco Fiorillo, Rosa Sanchez-Alvarez, Federica Sotgia, Michael P. Lisanti,

https://doi.org/10.18632/aging.101690 pp 4000—4023

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SNCA overexpression disturbs hippocampal gene expression trajectories in midlife

Thomas Hentrich, Zinah Wassouf, Olaf Riess, Julia M. Schulze-Hentrich,

https://doi.org/10.18632/aging.101691 pp 4024—4041

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Assessing onset, prevalence and survival in mice using a frailty phenotype

Cory W. Baumann, Dongmin Kwak, LaDora V. Thompson,

https://doi.org/10.18632/aging.101692 pp 4042—4053

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Association of gut microbiota composition and function with a senescence-accelerated mouse model of Alzheimer’s Disease using 16S rRNA gene and metagenomic sequencing analysis

Weijun Peng, Pengji Yi, Jingjing Yang, Panpan Xu, Yang Wang, Zheyu Zhang, Siqi Huang, Zhe Wang, Chunhu Zhang,

https://doi.org/10.18632/aging.101693 pp 4054—4065

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Diminished circulating retinol and elevated α-TOH/retinol ratio predict an increased risk of cognitive decline in aging Chinese adults, especially in subjects with ApoE2 or ApoE4 genotype

Xiaochen Huang, Huiqiang Zhang, Jie Zhen, Shengqi Dong, Yujie Guo, Nicholas Van Halm-Lutterodt, Linhong Yuan,

https://doi.org/10.18632/aging.101694 pp 4066—4083

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Two variants of Interleukin-1B gene are associated with the decreased risk, clinical features, and better overall survival of colorectal cancer: a two-center case-control study

Haihua Qian, Dan Zhang, Chuanqing Bao,

https://doi.org/10.18632/aging.101695 pp 4084—4092

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Putrescine delays postovulatory aging of mouse oocytes by upregulating PDK4 expression and improving mitochondrial activity

Wendan Xu, Lingjun Li, Jingwen Sun, Songyue Zhu, Zhengjie Yan, Li Gao, Chao Gao, Yugui Cui, Caiping Mao,

https://doi.org/10.18632/aging.101699 pp 4093—4106

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Comparisons of metastatic patterns of colorectal cancer among patients by age group: a population-based study

Lin Yang, Xingli Yang, Wenzhuo He, Shousheng Liu, Chang Jiang, Kunqian Xie, Kunwei Peng, Yafei You, Bei Zhang, Liangping Xia,

https://doi.org/10.18632/aging.101700 pp 4107—4119

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Overexpression of FoxM1 predicts poor prognosis of intrahepatic cholangiocarcinoma

Lingyun Liu, Jian Wu, Yu Guo, Wenxuan Xie, Bin Chen, Yi Zhang, Shaoqiang Li, Yunpeng Hua, Baogang Peng, Shunli Shen,

https://doi.org/10.18632/aging.101706 pp 4120—4140

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Naringin targets Zeb1 to suppress osteosarcoma cell proliferation and metastasis

He Ming, Qiu Chuang, Wang Jiashi, Li Bin, Wang Guangbin, Ji Xianglu,

https://doi.org/10.18632/aging.101710 pp 4141—4151

View Abstract PDF Full-Text How to Cite Special Collection on Cancer Therapeutics

Mechanistic insight into hyaluronic acid and platelet-rich plasma-mediated anti-inflammatory and anti-apoptotic activities in osteoarthritic mice

Chi-Sheng Chiou, Chi-Ming Wu, Navneet Kumar Dubey, Wen-Cheng Lo, Feng-Chou Tsai, Tran Dang Xuan Tung, Wei-Ching Hung, Wei-Che Hsu, Wei-Hong Chen, Win-Ping Deng,

https://doi.org/10.18632/aging.101713 pp 4152—4165

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Exercise training augments Sirt1-signaling and attenuates cardiac inflammation in D-galactose induced-aging rats

Wei-Kung Chen, Ying-Lan Tsai, Marthandam Asokan Shibu, Chia-Yao Shen, Shu Nu Chang-Lee, Ray-Jade Chen, Chun-Hsu Yao, Bo Ban, Wei-Wen Kuo, Chih-Yang Huang,

https://doi.org/10.18632/aging.101714 pp 4166—4174

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Melatonin alleviates meiotic defects in fetal mouse oocytes induced by Di (2-ethylhexyl) phthalate in vitro

Zhong-Yi Sun, Pan Zhang, Jun-Jie Wang, Jing-Cai Liu, Lan Li, Wei Shen, Qiu-Yue Zhai,

https://doi.org/10.18632/aging.101715 pp 4175—4187

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Fluoxetine-mediated inhibition of endoplasmic reticulum stress is involved in the neuroprotective effects of Parkinson’s disease

Tao Peng, Xiaoyan Liu, Jingtao Wang, Yu Liu, Zhenqiang FU, Xingrong Ma, Junmin Li, Guifang Sun, Yangfei Ji, Jingjing Lu, Wencui Wan, Hong Lu,

https://doi.org/10.18632/aging.101716 pp 4188—4196

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Hyperoside attenuates renal aging and injury induced by D-galactose via inhibiting AMPK-ULK1 signaling-mediated autophagy

Buhui Liu, Yue Tu, Weiming He, Yinglu Liu, Wei Wu, Qijun Fang, Haitao Tang, Renmao Tang, Ziyue Wan, Wei Sun, Yigang Wan,

https://doi.org/10.18632/aging.101723 pp 4197—4212

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Caloric restriction is associated with preservation of muscle strength in experimental cancer cachexia

Stef Levolger, Sandra van den Engel, Gisela Ambagtsheer, Jan N.M. IJzermans, Ron W.F. de Bruin,

https://doi.org/10.18632/aging.101724 pp 4213—4223

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ΔNp63 promotes IGF1 signalling through IRS1 in squamous cell carcinoma

Valentina Frezza, Claudia Fierro, Elena Gatti, Angelo Peschiaroli, Anna Maria Lena, Margherita Annicchiarico Petruzzelli, Eleonora Candi, Lucia Anemona, Alessandro Mauriello, Pier Giuseppe Pelicci, Gerry Melino, Francesca Bernassola,

https://doi.org/10.18632/aging.101725 pp 4224—4240

View Abstract PDF Full-Text How to Cite Special Collection on p53 Part 2

Circulating insulin-like growth factor-1: a new clue in the pathogenesis of age-related macular degeneration

Niccolò Castellino, Antonio Longo, Teresio Avitabile, Andrea Russo, Matteo Fallico, Vincenza Bonfiglio, Mario Damiano Toro, Robert Rejdak, Katarzyna Nowomiejska, Paolo Murabito, Claudio Furino, Michele Reibaldi,

https://doi.org/10.18632/aging.101727 pp 4241—4247

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How I treat elderly patients with plasma cell dyscrasias

Maria Gavriatopoulou, Despoina Fotiou, Ioannis Ntanasis-Stathopoulos, Efstathios Kastritis, Evangelos Terpos, Meletios Athanasios Dimopoulos,

https://doi.org/10.18632/aging.101707 pp 4248—4268

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Protein synthesis and quality control in aging

Aleksandra S. Anisimova, Alexander I. Alexandrov, Nadezhda E. Makarova, Vadim N. Gladyshev, Sergey E. Dmitriev,

https://doi.org/10.18632/aging.101721 pp 4269—4288

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Paradoxes of senolytics

Mikhail V. Blagosklonny,

https://doi.org/10.18632/aging.101750 pp 4289—4293

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Correction: The fasting blood glucose and long non-coding RNA SNHG8 predict poor prognosis in patients with gastric carcinoma after radical gastrectomy

Yunchai Lin, Dan Hu, Qiang Zhou, Xiandong Lin, Jinxiu Lin, Feng Peng,

https://doi.org/10.18632/aging.101755 pp 4294

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Featured Nobel Articles

Volume 10, Issue 12

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Editorials

Yosef Sarne,

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Itamar Lerner, Ravi Sojitra, Mark Gluck,

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Yasuo Miki, Janice L Holton, Koichi Wakabayashi,

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Indranil Biwas, Alireza R. Rezaie,

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A. Alia, Steffen Roßner,

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Dyonne Vos, Jan Albert Kuivenhoven, Bart van de Sluis,

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Bhupendar Tayal, Peter Sogaard,

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Zhichao Zhou, Jiangning Yang, John Pernow,

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Lisa Pauwels, Celine Maes, Stephan P. Swinnen,

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Kirsty Foote, Martin R. Bennett,

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Ryoko Umebayashi, Haruhito A. Uchida, Jun Wada,

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Magda R. Hamczyk, Ricardo Villa-Bellosta,

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Research Perspectives

Alan S. Green,

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Luigi Maiuri, Guido Kroemer,

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Research Papers

Liang Wang, Zhewei Wei, Kaiming Wu, Weigang Dai, Changhua Zhang, Jianjun Peng, Yulong He,

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Ying Wang, Pei Yin, Yi-Huan Chen, Yun-Sheng Yu, Wen-Xue Ye, Hao-Yue Huang, Zhen-Chun Ji, Zhen-Ya Shen,

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Zhiping Cai, Yapei Wu, Yao Li, Jizhong Ren, Linhui Wang,

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Liu Qian, Hui Zhang, Yuting Gu, Dechun Li, Songbing He, Hui Wang, Yiji Cheng, Wanlin Yang, Hongshuang Yu, Xiaonan Zhao, Wei Cai, Lijun Meng, Min Jin, Yanan Wang, Yanyun Zhang,

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Yu Zhang, Hong-Hui Wang, Xiang Wan, Yao Xu, Meng-Hao Pan, Shao-Chen Sun,

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