Exercise training augments Sirt1-signaling and attenuates cardiac inflammation in D-galactose induced-aging rats

Wei-Kung Chen; Ying-Lan Tsai; Marthandam Asokan Shibu; Chia-Yao Shen; Shu Nu Chang-Lee; Ray-Jade Chen; Chun-Hsu Yao; Bo Ban; Wei-Wen Kuo; Chih-Yang Huang

doi:doi:10.18632/aging.101714

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Research Paper Volume 10, Issue 12 pp 4166—4174

Exercise training augments Sirt1-signaling and attenuates cardiac inflammation in D-galactose induced-aging rats

Figure 4. Exercise enhances metabolic adaptation and attenuates inflammation in aging hearts. Long-term exercise training enhances SIRT1, PGC-1α and AMPK in aging hearts to provide protection against aging associated damages.