Research Paper Volume 10, Issue 12 pp 4197—4212

Figure 4. The actions of hyperoside, vitamin E and compound C on renal cellular aging and injury in vitro. (A, B) The NRK-52E cells were exposed to D-gal at 100 mM, with the treatment of hyperoside at 0, 5, and 10 μg/ml and VE at 50 μg/ml for 24 hours, and subjected to a WB analysis for p53, p21, IL-1 and TGF-β, respectively. (C, D) The NRK-52E cells were exposed to D-gal, with the treatment of hyperoside and CC for 24 hours, and subjected to a WB analysis for p53, p21, IL-1 and TGF-β, respectively. The data are expressed as the mean ± SD, (n=3), ^*P < 0.05, ^**P < 0.01. Abbreviation: D-gal, D-galactose; VE, vitamin E; WB, Western blot; IL-1, interleukin-1; TGF-β, transforming growth factor-β; CC, compound C.