Figure 1. Methylation levels (beta values mean ± SEM) of CpGs located at genes of the longevity-regulating pathway in relation to waist circumference categories after age and sex adjustments. Normal waist circumference vs High waist circumference levels, p<0.01**; p<0.001***; p<0.0001****. Cut-off value between both groups was 102 cm for men and 88 cm for women.