Featured Nobel Articles

Elizabeth Blackburn, a member of the Editorial Board of Aging, won the Nobel Prize in Physiology or Medicine 2009, while being a member of the board. Elizabeth Blackburn co-authored a paper published in the first (inaugural) issue of Aging.
Andrew V. Schally, Nobel Prize Laureate, published his paper in Aging.
Shinya Yamanaka won the Nobel Prize in Physiology and Medicine 2012. Shinya Yamanaka co-authored a paper published in Aging.

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Volume 11, Issue 6

31 March, 2019
pp 1602—1899

About the Cover

The cover features Figure 1 "CRABP-II expression is reduced in aged human and mouse skin" from Bielli et al.

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Editorials

GABAergic astrocytes in Alzheimer’s disease

Olga Garaschuk, Alexei Verkhratsky,

https://doi.org/10.18632/aging.101870 pp 1602—1604

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Mending the failing heart

Xiaowei Wang, Karlheinz Peter,

https://doi.org/10.18632/aging.101879 pp 1605—1606

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Risk indexation and atrial fibrillation

Thanh H. Nguyen, Tamila Heresztyn, John D. Horowitz,

https://doi.org/10.18632/aging.101889 pp 1607—1608

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Non-infarcted myocardium bears the weight in CVD

Hui Zhou, Hafisyatul Zainal, Valentina O. Puntmann,

https://doi.org/10.18632/aging.101890 pp 1609—1610

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From GWAS to new biology and treatments in CAD

Peter D. Jones, Tom R. Webb,

https://doi.org/10.18632/aging.101891 pp 1611—1612

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Saturated fatty acid-crystals activate NLRP3 inflammasome

Tadayoshi Karasawa, Masafumi Takahashi,

https://doi.org/10.18632/aging.101892 pp 1613—1614

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Novel lacto-peptides improve cognitive decline

Yasuhisa Ano, Hiroyuki Nakayama,

https://doi.org/10.18632/aging.101893 pp 1615—1616

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Risk stratification in hypertrophic cardiomyopathy

Milind Desai, Amgad Mentias,

https://doi.org/10.18632/aging.101895 pp 1617—1618

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Research Papers

Cellular retinoic acid binding protein-II expression and its potential role in skin aging

Alessandra Bielli, Maria Giovanna Scioli, Federico D’Amico, Chiara Tarquini, Sara Agostinelli, Gaetana Costanza, Elena Doldo, Elena Campione, Daniela Passeri, Filadelfo Coniglione, Augusto Orlandi,

https://doi.org/10.18632/aging.101813 pp 1619—1632

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Gene signatures and prognostic values of m6A regulators in clear cell renal cell carcinoma – a retrospective study using TCGA database

Jingcheng Zhou, Jiangyi Wang, Baoan Hong, Kaifang Ma, Haibiao Xie, Lei Li, Kenan Zhang, Bowen Zhou, Lin Cai, Kan Gong,

https://doi.org/10.18632/aging.101856 pp 1633—1647

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Modulation of soluble receptor for advanced glycation end-products (RAGE) isoforms and their ligands in healthy aging

Francesco Scavello, Filippo Zeni, Calogero C. Tedesco, Emanuela Mensà, Fabrizio Veglia, Antonio Domenico Procopio, Anna Rita Bonfigli, Fabiola Olivieri, Angela Raucci,

https://doi.org/10.18632/aging.101860 pp 1648—1663

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A comparison of the mitochondrial proteome and lipidome in the mouse and long-lived Pipistrelle bats

Amelia K. Pollard, Thomas L. Ingram, Catharine A. Ortori, Freya Shephard, Margaret Brown, Susan Liddell, David A. Barrett, Lisa Chakrabarti,

https://doi.org/10.18632/aging.101861 pp 1664—1685

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Trends in the incidence of recurrent stroke at 5 years after the first-ever stroke in rural China: a population-based stroke surveillance from 1992 to 2017

Wenjuan Zhao, Jialing Wu, Jie Liu, Yanan Wu, Jingxian Ni, Hongfei Gu, Jun Tu, Jinghua Wang, Zhongping An, Xianjia Ning,

https://doi.org/10.18632/aging.101862 pp 1686—1694

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Long non-coding RNA CDKN2B-AS1 reduces inflammatory response and promotes cholesterol efflux in atherosclerosis by inhibiting ADAM10 expression

Haocheng Li, Song Han, Qingfeng Sun, Ye Yao, Shiyong Li, Chao Yuan, Bo Zhang, Bao Jing, Jia Wu, Ye Song, Haiyang Wang,

https://doi.org/10.18632/aging.101863 pp 1695—1715

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Elevated FPR confers to radiochemoresistance and predicts clinical efficacy and outcome of metastatic colorectal cancer patients

Qing-Gen Chen, Lei Zhang, Fan Sun, Shu-Qi Li, Xia-Hong You, Yu-Huan Jiang, Wei-Ming Yang, Qiong-Hui Zhong, Xiao-Zhong Wang, Hou-Qun Ying,

https://doi.org/10.18632/aging.101864 pp 1716—1732

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Circulating GDF11 levels are decreased with age but are unchanged with obesity and type 2 diabetes

Juan Añón-Hidalgo, Victoria Catalán, Amaia Rodríguez, Beatriz Ramírez, Camilo Silva, Juan C. Galofré, Javier Salvador, Gema Frühbeck, Javier Gómez-Ambrosi,

https://doi.org/10.18632/aging.101865 pp 1733—1744

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H₂S restores the cardioprotective effects of ischemic post-conditioning by upregulating HB-EGF/EGFR signaling

Yuanzhou Zhang, Jun Gao, Weiming Sun, Xin Wen, Yuxin Xi, Yuehong Wang, Can Wei, Changqing Xu, Hongzhu Li,

https://doi.org/10.18632/aging.101866 pp 1745—1758

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Tubastatin A inhibits HDAC and Sirtuin activity rather than being a HDAC6-specific inhibitor in mouse oocytes

Yun-Jung Choi, Min-Hee Kang, Kwonho Hong, Jin-Hoi Kim,

https://doi.org/10.18632/aging.101867 pp 1759—1777

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Anesthesia and surgery induce cognitive dysfunction in elderly male mice: the role of gut microbiota

Gaofeng Zhan, Dongyu Hua, Niannian Huang, Yue Wang, Shan Li, Zhiqiang Zhou, Ning Yang, Riyue Jiang, Bin Zhu, Ling Yang, Fan Yu, Hui Xu, Chun Yang, Ailin Luo,

https://doi.org/10.18632/aging.101871 pp 1778—1790

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Muscle-derived miR-34a increases with age in circulating extracellular vesicles and induces senescence of bone marrow stem cells

Sadanand Fulzele, Bharati Mendhe, Andrew Khayrullin, Maribeth Johnson, Helen Kaiser, Yutao Liu, Carlos M. Isales, Mark W. Hamrick,

https://doi.org/10.18632/aging.101874 pp 1791—1803

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Endothelial cells secreted endothelin-1 augments diabetic nephropathy via inducing extracellular matrix accumulation of mesangial cells in ETBR^-/- mice

Hong-hong Zou, Li Wang, Xiao-xu Zheng, Gao-si Xu, Yunfeng Shen,

https://doi.org/10.18632/aging.101875 pp 1804—1820

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Reactivation of microRNA-506 inhibits gastric carcinoma cell metastasis through ZEB2

Gui-Jun Wang, Bao-Ping Jiao, Yang-Jun Liu, Yan-Rong Li, Bei-Bei Deng,

https://doi.org/10.18632/aging.101877 pp 1821—1831

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White light emitting diode induces autophagy in hippocampal neuron cells through GSK-3-mediated GR and RORα pathways

Yang Yang, Yimin Jia, Qinwei Sun, Haibo Dong, Ruqian Zhao,

https://doi.org/10.18632/aging.101878 pp 1832—1849

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Longitudinal assessment of health-span and pre-death morbidity in wild type Drosophila

Alexandros Gaitanidis, Agapi Dimitriadou, Harold Dowse, Subhabrata Sanyal, Carsten Duch, Christos Consoulas,

https://doi.org/10.18632/aging.101880 pp 1850—1873

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DNA methylation in genes of longevity-regulating pathways: association with obesity and metabolic complications

Francisca Salas-Pérez, Omar Ramos-Lopez, María L. Mansego, Fermín I. Milagro, José L. Santos, José I. Riezu-Boj, J. Alfredo Martínez,

https://doi.org/10.18632/aging.101882 pp 1874—1899

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