Research Paper Volume 11, Issue 14 pp 4801—4835

Figure 3. Ingenuity pathway analysis of differentially expressed proteins in co‐cultures compared to mixed cell populations. Ingenuity Pathway Analysis (IPA) showed canonical pathways significantly altered (p < 0.001). The p value for each pathway is indicated by the bar and is expressed as ‐1 times the log of the p value. Red colored bars indicate a predicted significant activation of the pathway (z‐score >2), whereas orange colored bars indicate a not significant activation (z‐score between 0 and 2). Green bars indicate a not significant inhibition of the pathway (z‐score between 0 and ‐2). White bars indicate that the pathway is altered, but it was not possible to predict whether it is activated nor inhibited.