Research Paper Volume 11, Issue 14 pp 5008—5034

Figure 2. Rb1 increases GABA_ARα1 and gephyrin expression in normal or MPP⁺-treated SH-SY5Y cell. (A) Effect of different concentrations of MPP⁺ on the expression of GABA_ARα1, GAD67, gephyrin, and PSD-95 in SH-SY5Y cell. (B) Effect of different concentrations of Rb1 on the expression of GABA_ARα1, GAD67, gephyrin, and PSD-95 in SH-SY5Y cell. (C) Effect of different concentrations of Rb1 on the expression of GABA_ARα1, gephyrin, and vGAT in 500 μM MPP⁺-treated SH-SY5Y cell. n = 3. Results are expressed as the mean ± SEM. ^**P < 0.01 and ^*P < 0.05 vs. control; ^##P < 0.01 and ^#P < 0.05 vs. MPP⁺ group. Statistical significance was determined by one-way ANOVA and the Bonferroni post-hoc test for pairwise comparisons.