Research Paper Volume 11, Issue 14 pp 5215—5231

Figure 5. IRF8 as the identification of IFTA-I between IFTA. (A) IRF8 expression had significant differences among the STA, IFTA and IFTA-I groups; ROC curve showed that IRF8 could be used for predicting IFTA-I from STA (B) and IFTA (C) and STA from IFTA (D); (E) All biopsies were divided into IRF8 high-expressed and low-expressed group and it indicated that recipients with high IRF8 expression were easier to develop into renal graft dysfunction and failure than that in the IRF8 low-expressed group (P < 0.00001); (F) AUC of IRF8 was 0.75 in the biopsies without rejection; (G) IRF8 expression was higher-expressed in the peripheral blood lymphocyte (PBL) in renal dysfunction w/o rejection than those with normal kidney function or with acute rejection in post-transplantation recipients. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001.