Research Paper Volume 11, Issue 16 pp 6014—6028
MiR-146b accelerates osteoarthritis progression by targeting alpha-2-macroglobulin
Figure 6. Effects of miR-146b on the homoeostasis of articular cartilage. Sections of articular cartilage from the mice were analysed by Immunostaining. Immunofluorescence stainings of (A) Collagen II, (B) Aggrecan. Immunohistochemical stainings of (C) MMP13 and (D) Cleaved Caspase-3. (E–G) The ratios of immunoreactive positive cells, Aggrecan (E), MMP13 (F) and Cleaved Caspase-3 (G) were analysed. Scale bar: 50μm. *P<0.05.