Figure 1. Changes in bodyweight. (A) The bodyweights before and after 12 weeks of feeding were compared between HFD rats and ND rats. (B) The bladder weights were compared between ND and HFD rats after 12 weeks of feeding. Data are expressed as the mean ± SEM, N = 40 per group, * P < 0.05 for ND vs. HFD. ND: normal diet; HFD: high-fat diet; W: week; NS: not significant.