Research Paper Volume 11, Issue 16 pp 6199—6216

Attenuated BK channel function promotes overactive bladder in a rat model of obesity

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Figure 3. The mRNA levels of the Kcnma1 and Kcnmb1 are significantly reduced in the DSM of HFD rats. The relative mRNA levels of Kcnma1 (A), Kcnmb1 (B) and Kcnmb4 (C) in DSM layers (Tissue) and isolated DSM cells (Single cell) were lower in the HFD group than in the ND group. Data are expressed as the mean ± SEM. Tissue: n = 16, N = 5 per group; Single cell: n = 16 (the number of strips to isolate cells), N = 5 per group. * P < 0.05 for ND vs. HFD. ND: normal diet; HFD: high-fat diet; NS: not significant.