Research Paper Volume 11, Issue 18 pp 7553—7569

Figure 2. Overexpression of TUG1 enhanced the sensitivity of NSCLC cells to DDP. (A) the expression level of TUG1 after transfection of pcDNA-TUG1 and si-TUG1 detected by qRT-PCR; (B) the IC50 values of DDP in SPC-A1 cells and H520 cells transfected with si-TUG1 and SPC-A1/DDP and H520/DDP cells transfected with pcDNA-TUG1; (C) colony forming ability of transfected cells in each group under DDP treatment detected by colony formation assay; (D) migration ability of transfected cells in each group under DDP treatment detected by scratch test; (E) the invasive ability of transfected cells in each group detected by Transwell assay; ** p < 0.01 versus the si-NC group.