The cover features Figure 7 "Schematic representation of the effects of the modulation of THs levels in healthspan and lifespan in mice" from López-Noriega et al.
Xu X, Chen X, Xu M, Liu X, Pan B, Qin J, Xu T, Zeng K, Pan Y, He B, Sun H, Sun L, Wang S, . miR-375-3p suppresses tumorigenesis and partially reverses chemoresistance by targeting YAP1 and SP1 in colorectal cancer cells. . 11:7357-7385. https://doi.org/10.18632/aging.102214
Zhou Y, Shi H, Du Y, Zhao G, Wang X, Li Q, Liu J, Ye L, Shen Z, Guo Y, Huang Y, . lncRNA DLEU2 modulates cell proliferation and invasion of non-small cell lung cancer by regulating miR-30c-5p/SOX9 axis. . 11:7386-7401. https://doi.org/10.18632/aging.102226
Wang P, Qi X, Xu G, Liu J, Guo J, Li X, Ma X, Sun H, . CCL28 promotes locomotor recovery after spinal cord injury via recruiting regulatory T cells. . 11:7402-7415. https://doi.org/10.18632/aging.102239
Lin X, Li G, Zhang Y, Zhao J, Lu J, Gao Y, Liu H, Li G, Yang T, Song L, Wu H, . Hearing consequences in Gjb2 knock-in mice: implications for human p.V37I mutation. . 11:7416-7441. https://doi.org/10.18632/aging.102246
Jing X, Liang H, Hao C, Hongxia L, Cui X, . Analyses of an epigenetic switch involved in the activation of pioneer factor FOXA1 leading to the prognostic value of estrogen receptor and FOXA1 co-expression in breast cancer. . 11:7442-7456. https://doi.org/10.18632/aging.102250
Hao Y, Ding J, Hong R, Bai S, Wang Z, Mo C, Hu Q, Li Z, Guan Y, . Increased interleukin-18 level contributes to the development and severity of ischemic stroke. . 11:7457-7472. https://doi.org/10.18632/aging.102253
Chen E, Qin X, Peng K, Li Q, Tang C, Wei Y, Yu S, Gan L, Liu T, . HnRNPR-CCNB1/CENPF axis contributes to gastric cancer proliferation and metastasis. . 11:7473-7491. https://doi.org/10.18632/aging.102254
Qiu T, Tian Y, Gao Y, Ma M, Li H, Liu X, Wu H, Zhang Y, Ding H, Cao M, Zhang J, Dai J, Chen J, et al, . PTEN loss regulates alveolar epithelial cell senescence in pulmonary fibrosis depending on Akt activation. . 11:7492-7509. https://doi.org/10.18632/aging.102262
Chen T, Zhang Y, Liu Y, Zhu D, Yu J, Li G, Sun Z, Wang W, Jiang H, Hong Z, . MiR-27a promotes insulin resistance and mediates glucose metabolism by targeting PPAR-γ-mediated PI3K/AKT signaling. . 11:7510-7524. https://doi.org/10.18632/aging.102263
Lai J, Chen B, Zhang G, Wang Y, Mok H, Wen L, Pan Z, Su F, Liao N, . Identification of a novel microRNA recurrence-related signature and risk stratification system in breast cancer. . 11:7525-7536. https://doi.org/10.18632/aging.102268
Ma J, Shi C, Liu Z, Han B, Guo L, Zhu L, Ye T, . Hydrogen sulfide is a novel regulator implicated in glucocorticoids-inhibited bone formation. . 11:7537-7552. https://doi.org/10.18632/aging.102269
Guo S, Zhang L, Zhang Y, Wu Z, He D, Li X, Wang Z, . Long non-coding RNA TUG1 enhances chemosensitivity in non-small cell lung cancer by impairing microRNA-221-dependent PTEN inhibition. . 11:7553-7569. https://doi.org/10.18632/aging.102271
Su Q, Zhang P, Yu D, Wu Z, Li D, Shen F, Liao P, Yin G, . Upregulation of miR-93 and inhibition of LIMK1 improve ventricular remodeling and alleviate cardiac dysfunction in rats with chronic heart failure by inhibiting RhoA/ROCK signaling pathway activation. . 11:7570-7586. https://doi.org/10.18632/aging.102272
Hart CR, Ryan ZC, Pfaffenbach KT, Dasari S, Parvizi M, Lalia AZ, Lanza IR, . Attenuated activation of the unfolded protein response following exercise in skeletal muscle of older adults. . 11:7587-7604. https://doi.org/10.18632/aging.102273
Cao Z, Wang R, Cheng Y, Yang H, Li S, Sun L, Xu W, Wang Y, . Adherence to a healthy lifestyle counteracts the negative effects of risk factors on all-cause mortality in the oldest-old. . 11:7605-7619. https://doi.org/10.18632/aging.102274
Li H, Wang X, Lu X, Zhu H, Li S, Duan S, Zhao X, Zhang F, Alterovitz G, Wang F, Li Q, Tian X, Xu M, . Co-expression network analysis identified hub genes critical to triglyceride and free fatty acid metabolism as key regulators of age-related vascular dysfunction in mice. . 11:7620-7638. https://doi.org/10.18632/aging.102275
Xu X, Tao Y, Niu Y, Wang Z, Zhang C, Yu Y, Ma L, . miR-125a-5p inhibits tumorigenesis in hepatocellular carcinoma. . 11:7639-7662. https://doi.org/10.18632/aging.102276
Deng G, Xu N, Huang Q, Tan J, Zhang Z, Li X, Wei J, . Association between promoter DNA methylation and gene expression in the pathogenesis of ischemic stroke. . 11:7663-7677. https://doi.org/10.18632/aging.102278
Li S, Liu F, Pei Y, Wang W, Zheng K, Zhang X, . Long noncoding RNA TTN-AS1 enhances the malignant characteristics of osteosarcoma by acting as a competing endogenous RNA on microRNA-376a thereby upregulating dickkopf-1. . 11:7678-7693. https://doi.org/10.18632/aging.102280
Ho A, Sinick J, Esko T, Fischer K, Menni C, Zierer J, Matey-Hernandez M, Fortney K, Morgen EK, . Circulating glucuronic acid predicts healthspan and longevity in humans and mice. . 11:7694-7706. https://doi.org/10.18632/aging.102281
Wang Q, Tan Y, Fang C, Zhou J, Wang Y, Zhao K, Jin W, Wu Y, Liu X, Liu X, Kang C, . Single-cell RNA-seq reveals RAD51AP1 as a potent mediator of EGFRvIII in human glioblastomas. . 11:7707-7722. https://doi.org/10.18632/aging.102282
Rong Y, Liu W, Lv C, Wang J, Luo Y, Jiang D, Li L, Zhou Z, Zhou W, Li Q, Yin G, Yu L, Fan J, et al, . Neural stem cell small extracellular vesicle-based delivery of 14-3-3t reduces apoptosis and neuroinflammation following traumatic spinal cord injury by enhancing autophagy by targeting Beclin-1. . 11:7723-7745. https://doi.org/10.18632/aging.102283
Livia López-Noriega, Vivian Capilla-González, Nadia Cobo-Vuilleumier, Eugenia Martin-Vazquez, Petra Isabel Lorenzo, Enrique Martinez-Force, Mario Soriano-Navarro, María García-Fernández, Silvana Yanina Romero-Zerbo, Francisco Javier Bermúdez-Silva, Irene Díaz-Contreras, Ana Sánchez-Cuesta, Carlos Santos-Ocaña, Abdelkrim Hmadcha, Bernat Soria, Franz Martín, Benoit Raymond Gauthier, Alejandro Martin-Montalvo,
López-Noriega L, Capilla-González V, Cobo-Vuilleumier N, Martin-Vazquez E, Lorenzo PI, Martinez-Force E, Soriano-Navarro M, García-Fernández M, Romero-Zerbo SY, Bermúdez-Silva FJ, Díaz-Contreras I, Sánchez-Cuesta A, Santos-Ocaña C, et al, . Inadequate control of thyroid hormones sensitizes to hepatocarcinogenesis and unhealthy aging. . 11:7746-7779. https://doi.org/10.18632/aging.102285
Shan L, Liu W, Zhan Y, . Sulfated polysaccharide of Sepiella maindroni ink targets Akt and overcomes resistance to the FGFR inhibitor AZD4547 in bladder cancer. . 11:7780-7795. https://doi.org/10.18632/aging.102286
Patrick Lebok, Aurelia von Hassel, Jan Meiners, Claudia Hube-Magg, Ronald Simon, Doris Höflmayer, Andrea Hinsch, David Dum, Christoph Fraune, Cosima Göbel, Katharina Möller, Guido Sauter, Frank Jacobsen, Franziska Büscheck, Kristina Prien, Till Krech, Rainer Horst Krech, Albert von der Assen, Linn Wölber, Isabell Witzel, Barbara Schmalfeldt, Stefan Geist, Peter Paluchoswski, Christian Wilke, Uwe Heilenkötter, Luigi Terracciano, Volkmar Müller, Waldemar Wilczak, Eike Christian Burandt,
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Lin Y, Zhang M, Lu Q, Xie J, Wu J, Chen C, . A novel chalcone derivative exerts anti-inflammatory and anti-oxidant effects after acute lung injury. . 11:7805-7816. https://doi.org/10.18632/aging.102288
Xu J, Wu W, Tang Y, Lin Y, Xue Y, Hu J, Lin D, . PRL-3 exerts oncogenic functions in myeloid leukemia cells via aberrant dephosphorylation of stathmin and activation of STAT3 signaling. . 11:7817-7829. https://doi.org/10.18632/aging.102290
Liu J, Yao L, Zhang M, Jiang J, Yang M, Wang Y, . Downregulation of LncRNA-XIST inhibited development of non-small cell lung cancer by activating miR-335/SOD2/ROS signal pathway mediated pyroptotic cell death. . 11:7830-7846. https://doi.org/10.18632/aging.102291
Ji F, Liu Y, Hao J, Wang L, Dai M, Shen G, Yan X, . KLB gene polymorphism is associated with obesity and non-alcoholic fatty liver disease in the Han Chinese. . 11:7847-7858. https://doi.org/10.18632/aging.102293
Stefan Steurer, Benjamin Hager, Franziska Büscheck, Doris Höflmayer, Maria Christina Tsourlakis, Sarah Minner, Till S. Clauditz, Claudia Hube-Magg, Andreas M. Luebke, Ronald Simon, Jakob R. Izbicki, Eike Burandt, Guido Sauter, Christoph Fraune, Sören Weidemann, Thorsten Schlomm, Hans Heinzer, Alexander Haese, Markus Graefen, Hartwig Huland, Asmus Heumann,
Javier Donate-Correa, Ernesto Martín-Núñez, Carolina Hernández-Carballo, Carla Ferri, Víctor G. Tagua, Alejandro Delgado-Molinos, Ángel López-Castillo, Sergio Rodríguez-Ramos, Purificación Cerro-López, Victoria Castro López-Tarruella, Raquel Felipe-García, Miguel A. Arévalo-Gomez, Nayra Pérez-Delgado, Carmen Mora-Fernández, Juan F. Navarro-González,
Bani Hassan E, Alderghaffar M, Wauquier F, Coxam V, Demontiero O, Vogrin S, Wittrant Y, Duque G, . The effects of dietary fatty acids on bone, hematopoietic marrow and marrow adipose tissue in a murine model of senile osteoporosis. . 11:7938-7947. https://doi.org/10.18632/aging.102299
Liu D, Ma Z, Yang J, Zhao M, Ao H, Zheng X, Wen Q, Yang Y, You J, Qiao S, Yuan J, . Prevalence and prognosis significance of cardiovascular disease in cancer patients: a population-based study. . 11:7948-7960. https://doi.org/10.18632/aging.102301
Wang Y, Zuo R, Wang Z, Luo L, Wu J, Zhang C, Liu M, Shi C, Zhou Y, . Kinsenoside ameliorates intervertebral disc degeneration through the activation of AKT-ERK1/2-Nrf2 signaling pathway. . 11:7961-7977. https://doi.org/10.18632/aging.102302
Wei Z, Mahaman YAR, Zhu F, Wu M, Xia Y, Zeng K, Yang Y, Liu R, Wang J, Shu X, Wang X, . GSK-3β and ERK1/2 incongruously act in tau hyperphosphorylation in SPS-induced PTSD rats. . 11:7978-7995. https://doi.org/10.18632/aging.102303
Huang R, Qin C, Wang J, Hu Y, Zheng G, Qiu G, Ge M, Tao H, Shu Q, Xu J, . Differential effects of extracellular vesicles from aging and young mesenchymal stem cells in acute lung injury. . 11:7996-8014. https://doi.org/10.18632/aging.102314
Cao Z, Gao D, Xu T, Zhang L, Tong X, Zhang D, Wang Y, Ning W, Qi X, Ma Y, Ji K, Yu T, Li Y, et al, . Circular RNA profiling in the oocyte and cumulus cells reveals that circARMC4 is essential for porcine oocyte maturation. . 11:8015-8034. https://doi.org/10.18632/aging.102315
Yang C, Jiao Y, Wei B, Yang Z, Wu J, Jensen J, Jean W, Huang C, Kuo C, . Correction for: Aged cells in human skeletal muscle after resistance exercise. . 11:8035-8035. https://doi.org/10.18632/aging.102338