Figure 4. Circadian clock associates with the immune infiltrates and PD-L1 immune checkpoint. (A, B) Circadian genes were correlated with CD8 T cells and CD4 T cells. (C) CD8A expression was time-dependent. (D) The circadian rhythm of PD-L1. Abbreviations: LUAD, lung adenocarcinoma; LUSC, lung squamous cell carcinoma.