Studies on APP metabolism related to age-associated mitochondrial dysfunction in APP/PS1 transgenic mice

Lizhi Chen; Shicheng Xu; Tong Wu; Yijia Shao; Li Luo; Lingqi Zhou; Shanshan Ou; Hai Tang; Wenhua Huang; Kaihua Guo; Jie Xu

doi:doi:10.18632/aging.102451

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Research Paper Volume 11, Issue 22 pp 10242—10251

Studies on APP metabolism related to age-associated mitochondrial dysfunction in APP/PS1 transgenic mice

Figure 1. Hippocampal and platelets ATP content in and from APP/PS1 transgenic mice and C57 mice. (A) ATP content in hippocampi; (B) ATP content in platelets. Results are expressed as a mean ± SD value of six experiments measured in duplicate. The values are expressed as percentage of control, which is set to 100%. ^**P < 0.01 vs. C57 (6 months), ^##P < 0.01 vs. APP/PS1 (6 months), ⁺⁺P < 0.01 vs. C57 (10 months).