Research Paper Volume 11, Issue 24 pp 12345—12360

Circular RNA SMO sponges miR-338-3p to promote the growth of glioma by enhancing the expression of SMO

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Figure 6. SMO has same effect on cells activity as circSMO742. (A, B) SMO knockdown inhibited SMO mRNA expression while the presence of circSMO742 or miR-338-3p inhibitor could reverse the expression caused by SMO knockdown. (CF) SMO suppression suppressed proliferation, migration, invasion but promoted apoptosis of U-87 MG cells. *P<0.05, v.s. NC.