Research Paper Volume 11, Issue 24 pp 12810—12821

Nicotine instigates podocyte injury via NLRP3 inflammasomes activation

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Figure 4. Inhibition of inflammasome abolishes nicotine-induced podocyte injury. Representative immunofluorescence images and summarized quantification data shows Podocin (A) and Nephrin (B) expression in podocytes treated with or without stimulation of nicotine and/or WEHD. Images were quantified using Image J software. N=5. *significant difference from control, #significant difference from nicotine treated group.