Research Paper Volume 12, Issue 7 pp 5948—5976

Figure 2. miR-10a-5p is upregulated in OA and acts as a potential promising biomarker. (A) The relative expression of miR-10a-5p in OA and control cartilage tissues analyzed by RT-qPCR (8 OA cartilage vs. 7 control cartilage, **P < 0.01); (B) The relative expression of miR-10a-5p in OA and control PBMC analyzed by RT-qPCR (8 OA cartilage vs. 8 control cartilage, *P < 0.05); (C) ROC analysis of miR-10a-5p in PBMC for the diagnosis of OA (AUC,0.84; P=0.02); Representative pictures of articular cartilage in sham group (D left) and DMM group (D right) stained by H&E. Scale bar, 200 um. (E) The relative expression of miR-10a-5p in sham group and DMM group analyzed by RT-qPCR (6 sham vs. 6 DMM cartilage, **P < 0.01).