Zhao J, Li G, Zhao X, Lin X, Gao Y, Raimundo N, Li G, Shang W, Wu H, Song L, . Down-regulation of AMPK signaling pathway rescues hearing loss in TFB1 transgenic mice and delays age-related hearing loss. . 12:5590-5611. https://doi.org/10.18632/aging.102977
Albers E, Avram A, Sbroggio M, Fernandez-Capetillo O, Lopez-Contreras AJ, . Supraphysiological protection from replication stress does not extend mammalian lifespan. . 12:5612-5624. https://doi.org/10.18632/aging.103039
Li R, Li B, Shen M, Cao Y, Zhang X, Li W, Tao J, Wu W, Liu H, . LncRNA 2310043L19Rik inhibits differentiation and promotes proliferation of myoblast by sponging miR-125a-5p. . 12:5625-5639. https://doi.org/10.18632/aging.102905
Zhang Y, Liu X, Zhang J, Xu Y, Shao J, Hu Y, Shu P, Cheng H, . Inhibition of miR-19a partially reversed the resistance of colorectal cancer to oxaliplatin via PTEN/PI3K/AKT pathway. . 12:5640-5650. https://doi.org/10.18632/aging.102929
Chen Y, Zhang L, Ren J, Zhang Y, Wu N, Jia M, Yu Y, Ning Z, Tang C, Qi Y, . Intermedin1-53 attenuates aging-associated vascular calcification in rats by upregulating sirtuin 1. . 12:5651-5674. https://doi.org/10.18632/aging.102934
Tan C, Dai Y, Liu X, Zhao G, Wang W, Li J, Qi L, . STAT5A induced LINC01198 promotes proliferation of glioma cells through stabilizing DGCR8. . 12:5675-5692. https://doi.org/10.18632/aging.102938
Al-Azab M, Wang B, Elkhider A, Walana W, Li W, Yuan B, Ye Y, Tang Y, Almoiliqy M, Adlat S, Wei J, Zhang Y, Li X, . Indian Hedgehog regulates senescence in bone marrow-derived mesenchymal stem cell through modulation of ROS/mTOR/4EBP1, p70S6K1/2 pathway. . 12:5693-5715. https://doi.org/10.18632/aging.102958
Chen X, Wang C, Yang P, Shi L, Wang H, . Ube2s-stabilized β-catenin protects against myocardial ischemia/reperfusion injury by activating HIF-1α signaling. . 12:5716-5732. https://doi.org/10.18632/aging.102960
Zhi J, Yi J, Tian M, Wang H, Kang N, Zheng X, Gao M, . Immune gene signature delineates a subclass of thyroid cancer with unfavorable clinical outcomes. . 12:5733-5750. https://doi.org/10.18632/aging.102963
Cai M, Ou X, Li Y, Zou X, Xu Z, Wang Y, Peng H, Deng Y, Guo Y, Lu M, Gan W, Peng T, Li M, . Molecular anatomy of the subcellular localization and nuclear import mechanism of herpes simplex virus 1 UL6. . 12:5751-5763. https://doi.org/10.18632/aging.102965
Lin Y, Chen M, Hsieh T, Liou J, Chen C, . CK1δ as a potential therapeutic target to treat bladder cancer. . 12:5764-5780. https://doi.org/10.18632/aging.102966
Jiong Yu, Xiaowei Shi, Chunzhang Yang, Petra Bullova, Christopher S. Hong, Cody L. Nesvick, Pauline Dmitriev, Karel Pacak, Zhengping Zhuang, Hongcui Cao, Lanjuan Li,
Yu J, Shi X, Yang C, Bullova P, Hong CS, Nesvick CL, Dmitriev P, Pacak K, Zhuang Z, Cao H, Li L, . A novel germline gain-of-function HIF2A mutation in hepatocellular carcinoma with polycythemia. . 12:5781-5791. https://doi.org/10.18632/aging.102967
Hong M, Zhu H, Sun Q, Zhu Y, Miao Y, Yang H, Qiu H, Li J, Qian S, . Decitabine in combination with low-dose cytarabine, aclarubicin and G-CSF tends to improve prognosis in elderly patients with high-risk AML. . 12:5792-5811. https://doi.org/10.18632/aging.102973
Huang Q, Chen Y, Shen S, Wang Y, Liu L, Wu S, Xu W, Zhao W, Lin M, Wu J, . Klotho antagonizes pulmonary fibrosis through suppressing pulmonary fibroblasts activation, migration, and extracellular matrix production: a therapeutic implication for idiopathic pulmonary fibrosis. . 12:5812-5831. https://doi.org/10.18632/aging.102978
Lin K, Huang J, Luo H, Luo C, Zhu X, Bu F, Xiao H, Xiao L, Zhu Z, . Development of a prognostic index and screening of potential biomarkers based on immunogenomic landscape analysis of colorectal cancer. . 12:5832-5857. https://doi.org/10.18632/aging.102979
Ma M, Wan X, Gao M, Pan B, Chen D, Sun Q, Zhang M, Zhou C, Li T, Pan H, Shao W, Liu Z, Chen Y, et al, . Renin-angiotensin-aldosterone system blockade is associated with higher risk of contrast-induced acute kidney injury in patients with diabetes. . 12:5858-5877. https://doi.org/10.18632/aging.102982
Zhao D, Zhang C, Jiang M, Wang Y, Liang Y, Wang L, Qin K, Rehman FU, Zhang X, . Survival-associated alternative splicing signatures in non-small cell lung cancer. . 12:5878-5893. https://doi.org/10.18632/aging.102983
Ji F, Yang C, Li X, Zhang L, Yang M, Li J, Gao H, Zhu T, Cheng M, Li W, Wu S, Zhong A, Wang K, . Risk of breast cancer-related death in women with a prior cancer. . 12:5894-5906. https://doi.org/10.18632/aging.102984
Liang J, Li Y, Liu H, Zhang S, Wang M, Chu Y, Ye J, Xi Q, Zhao X, . Increased intrinsic default-mode network activity as a compensatory mechanism in aMCI: a resting-state functional connectivity MRI study. . 12:5907-5919. https://doi.org/10.18632/aging.102986
Konstantin G. Arbeev, Olivia Bagley, Svetlana V. Ukraintseva, Deqing Wu, Hongzhe Duan, Alexander M. Kulminski, Eric Stallard, Kaare Christensen, Joseph H. Lee, Bharat Thyagarajan, Joseph M. Zmuda, Anatoliy I. Yashin,
Arbeev KG, Bagley O, Ukraintseva SV, Wu D, Duan H, Kulminski AM, Stallard E, Christensen K, Lee JH, Thyagarajan B, Zmuda JM, Yashin AI, . Genetics of physiological dysregulation: findings from the long life family study using joint models. . 12:5920-5947. https://doi.org/10.18632/aging.102987
Li H, Xu X, Lin N, Wang D, Lin Y, Su Z, Lu H, . Overexpression of miR-10a-5p facilitates the progression of osteoarthritis. . 12:5948-5976. https://doi.org/10.18632/aging.102989
Huang D, Yan X, Fan S, Chen X, Yan J, Dong Q, Chen W, Liu N, Chen X, Yu Z, . Nrf2 deficiency promotes the increasing trend of autophagy during aging in skeletal muscle: a potential mechanism for the development of sarcopenia. . 12:5977-5991. https://doi.org/10.18632/aging.102990
Zhao H, Chen M, Wang J, Cao G, Chen W, Xu J, . PCNA-associated factor KIAA0101 transcriptionally induced by ELK1 controls cell proliferation and apoptosis in nasopharyngeal carcinoma: an integrated bioinformatics and experimental study. . 12:5992-6017. https://doi.org/10.18632/aging.102991
Wang H, Ma K, Liu H, Zhou J, . Reversal of multidrug resistance in leukemia cells using a transferrin-modified nanomicelle encapsulating both doxorubicin and psoralen. . 12:6018-6029. https://doi.org/10.18632/aging.102992
Yang Z, Shi J, He Z, LĂĽ Y, Xu Q, Ye C, Chen S, Tang B, Yin K, Lu Y, Chen X, . Predictors for imaging progression on chest CT from coronavirus disease 2019 (COVID-19) patients. . 12:6037-6048. https://doi.org/10.18632/aging.102999
Wang B, Li R, Lu Z, Huang Y, . Does comorbidity increase the risk of patients with COVID-19: evidence from meta-analysis. . 12:6049-6057. https://doi.org/10.18632/aging.103000
Liu Y, Nong L, Jia Y, Tan A, Duan L, Lu Y, Zhao J, . Aspirin alleviates hepatic fibrosis by suppressing hepatic stellate cells activation via the TLR4/NF-κB pathway. . 12:6058-6066. https://doi.org/10.18632/aging.103002
Zhang Y, Liu H, Liu X, Guo Y, Wang Y, Dai Y, Zhuo J, Wu B, Wang H, Zhang X, . Identification of an exosomal long non-coding RNAs panel for predicting recurrence risk in patients with colorectal cancer. . 12:6067-6088. https://doi.org/10.18632/aging.103006
Dai X, Hong L, Shen H, Du Q, Ye Q, Chen X, Zhang J, . Estradiol-induced senescence of hypothalamic astrocytes contributes to aging-related reproductive function declines in female mice. . 12:6089-6108. https://doi.org/10.18632/aging.103008
Wang X, She C, Li Q, Zhang D, Xu J, Li M, Li P, Xu H, . Ginsenoside Rh3 activates Nrf2 signaling and protects endometrial cells from oxygen and glucose deprivation-reoxygenation. . 12:6109-6119. https://doi.org/10.18632/aging.103009
Ye C, Li H, Bao M, Zhuo R, Jiang G, Wang W, . Alveolar macrophage - derived exosomes modulate severity and outcome of acute lung injury. . 12:6120-6128. https://doi.org/10.18632/aging.103010
Wang Y, Sun L, Qiu W, Qi W, Qi Y, Liu Z, Liu S, Lv J, . Inhibiting Forkhead box K1 induces autophagy to reverse epithelial-mesenchymal transition and metastasis in gastric cancer by regulating Myc-associated zinc finger protein in an acidic microenvironment. . 12:6129-6150. https://doi.org/10.18632/aging.103013
Wei G, Zhang T, Li Z, Yu N, Xue X, Zhou D, Chen Y, Zhang L, Yao X, Ji G, . USF1-mediated upregulation of lncRNA GAS6-AS2 facilitates osteosarcoma progression through miR-934/BCAT1 axis. . 12:6172-6190. https://doi.org/10.18632/aging.103015
Zhang Y, Sun J, Qi Y, Wang Y, Ding Y, Wang K, Zhou Q, Wang J, Ma F, Zhang J, Guo B, . Long non-coding RNA TPT1-AS1 promotes angiogenesis and metastasis of colorectal cancer through TPT1-AS1/NF90/VEGFA signaling pathway. . 12:6191-6205. https://doi.org/10.18632/aging.103016
Zheng W, Cui B, Sun Z, Li X, Han X, Yang Y, Li K, Hu L, Wang Z, , . Application of Generalized Split Linearized Bregman Iteration algorithm for Alzheimer's disease prediction. . 12:6206-6224. https://doi.org/10.18632/aging.103017
Zhan T, Wang X, Ouyang Z, Yao Y, Xu J, Liu S, Liu K, Deng Q, Wang Y, Zhao Y, . Rotating magnetic field ameliorates experimental autoimmune encephalomyelitis by promoting T cell peripheral accumulation and regulating the balance of Treg and Th1/Th17. . 12:6225-6239. https://doi.org/10.18632/aging.103018
Gao J, Xia R, Chen J, Gao J, Luo X, Ke C, Ren C, Li J, Mi Y, . Inhibition of esophageal-carcinoma cell proliferation by genistein via suppression of JAK1/2-STAT3 and AKT/MDM2/p53 signaling pathways. . 12:6240-6259. https://doi.org/10.18632/aging.103019
GarcĂa-Puga M, Saenz-Antoñanzas A, Fernández-TorrĂłn R, Munain ALd, Matheu A, . Myotonic Dystrophy type 1 cells display impaired metabolism and mitochondrial dysfunction that are reversed by metformin. . 12:6260-6275. https://doi.org/10.18632/aging.103022
Lin Z, Lin Y, Zhang Z, Shen J, Yang C, Jiang M, Hou Y, . Systematic analysis of bacteriostatic mechanism of flavonoids using transcriptome and its therapeutic effect on vaginitis. . 12:6292-6305. https://doi.org/10.18632/aging.103024
Chen X, Xu C, Liang H, Xi Z, Pan J, Yang Y, Sun Q, Yang G, Sun Y, Bian L, . Bone marrow mesenchymal stem cells transplantation alleviates brain injury after intracerebral hemorrhage in mice through the Hippo signaling pathway. . 12:6306-6323. https://doi.org/10.18632/aging.103025
Du T, Zhu G, Chen Y, Shi L, Liu D, Liu Y, Zhang X, Zhang J, . Anterior thalamic nucleus stimulation protects hippocampal neurons by activating autophagy in epileptic monkeys. . 12:6324-6339. https://doi.org/10.18632/aging.103026
Ma L, He H, Jiang K, Jiang P, He H, Feng S, Chen K, Shao J, Deng G, . FAM46C inhibits cell proliferation and cell cycle progression and promotes apoptosis through PTEN/AKT signaling pathway and is associated with chemosensitivity in prostate cancer. . 12:6352-6369. https://doi.org/10.18632/aging.103030
Yao G, Man Y, Li A, Guo Y, Dai Y, Wang P, Zhou Y, . NO up-regulates migraine-related CGRP via activation of an Akt/GSK-3β/NF-κB signaling cascade in trigeminal ganglion neurons. . 12:6370-6384. https://doi.org/10.18632/aging.103031
Bian W, Jing X, Yang Z, Shi Z, Chen R, Xu A, Wang N, Jiang J, Yang C, Zhang D, Li L, Wang H, Wang J, et al, . Downregulation of LncRNA NORAD promotes Ox-LDL-induced vascular endothelial cell injury and atherosclerosis. . 12:6385-6400. https://doi.org/10.18632/aging.103034
Xu T, Li H, Dai Z, Lau GK, Li B, Zhu W, Liu X, Liu H, Cai W, Huang S, Wang Q, Zhang S, . Spermidine and spermine delay brain aging by inducing autophagy in SAMP8 mice. . 12:6401-6414. https://doi.org/10.18632/aging.103035
Cong L, Gao Z, Zheng Y, Ye T, Wang Z, Wang P, Li M, Dong B, Yang W, Li Q, Qiao S, Wang C, Shen Y, et al, . Electrical stimulation inhibits Val-boroPro-induced pyroptosis in THP-1 macrophages via sirtuin3 activation to promote autophagy and inhibit ROS generation. . 12:6415-6435. https://doi.org/10.18632/aging.103038
Chai D, Yan J, Li C, Sun Y, Jiang H, . Sevoflurane inhibits neuronal migration and axon growth in the developing mouse cerebral cortex. . 12:6436-6455. https://doi.org/10.18632/aging.103041
Li S, He J, Liu Y, Yang J, . FGF22 promotes generation of ribbon synapses through downregulating MEF2D. . 12:6456-6466. https://doi.org/10.18632/aging.103042
Li R, Toan S, Zhou H, . Role of mitochondrial quality control in the pathogenesis of nonalcoholic fatty liver disease. . 12:6467-6485. https://doi.org/10.18632/aging.102972
Lan Ye, Anne L. Widlund, Carrie A. Sims, Dudley W. Lamming, Yuxia Guan, James G. Davis, David M. Sabatini, David E. Harrison, Ole Vang, Joseph A. Baur,
Ye L, Widlund AL, Sims CA, Lamming DW, Guan Y, Davis JG, Sabatini DM, Harrison DE, Vang O, Baur JA, . Correction for: Rapamycin doses sufficient to extend lifespan do not compromise muscle mitochondrial content or endurance. . 12:6486-6487. https://doi.org/10.18632/aging.102976
Hu M, Yu Z, Mei P, Li J, Luo D, Zhang H, Zhou M, Liang F, Chen R, . Correction for: Lycorine induces autophagy-associated apoptosis by targeting MEK2 and enhances vemurafenib activity in colorectal cancer. . 12:6488-6489. https://doi.org/10.18632/aging.103011