Figure 1. Pairwise linkage disequilibrium between circFOXO3 variants. CircFOXO3 derived from the third exon of the FOXO3 gene. Arrows indicate the locations of the SNPs. Linkage disequilibrium analysis revealed that the two tagSNPs at circFOXO3 flanking introns were located in the same haplotypic block. Numbers within squares indicate the D' value reported as a percentile.