Research Paper Volume 12, Issue 13 pp 13090—13114
Changes of saliva microbiota in the onset and after the treatment of diabetes in patients with periodontitis
Figure 3. Changes of the salivary microbiota under the circumstance of diabetes and treatments. (A and B) The salivary microbiome in healthy people (Group A) and naïve diabetic patients (Group B) as well as diabetes treated with metformin (Group C) and combined medication (Group D) were compared at the phylum level; (C and D) the amount of three genera (Blautia, Cobetia and Nocardia) and four species (Blautia_wexlerae, Lactobacillus_fermentum, Nocardia_coeliaca and Selenomonas_artemidis) with relatively high abundance in the naïve diabetic patients were significantly different from both healthy people and the treatment groups; (E and F) |Spearman correlation| ≥0.7 and q value≤0.01 analysis of the salivary microbiota at the genus and species levels with the abundance ≥ 0.02%.