Research Paper Volume 12, Issue 13 pp 13488—13501

Figure 2. TRIM29 promotes metastasis and proliferation of lung squamous cell carcinoma cells in vitro. (A) Western blot analysis of TRIM29 expression in HNBE, HTB-182, CRL-5889, SK-MES-1, NCL-H520, and NCL-H1915. (B) Overexpresson of TRIM29 could significantly promote the proliferation of HTB-182 cells. (C) Knockdown of TRIM29 could significantly inhibit the proliferation of NCI-H1915 cells. (D) Colony formation analysis of TRIM29 over-expression treated HTB-182 cells. (E) Western blot analysis of cell proliferation-related biomarkers expression in TRIM29 over-expression treated HTB-182 cells. (F) Colony formation analysis of TRIM29 knockdown treated NCI-H1915 cells. (G) Western blot analysis of cell proliferation-related biomarkers expression in TRIM29 knockdown treated NCI-H1915 cells. (H) Migration and invasion analysis of TRIM29 over-expression treated HTB-182 cells. (I) Western blot analysis of EMT-related biomarkers expression in RIM29 over-expression treated HTB-182 cells. (J) Migration and invasion analysis of TRIM29 knockdown treated NCI-H1915 cells. (K) Western blot analysis of EMT-related biomarkers expression in knockdown treated NCI-H1915 cells. **P<0.01, ***P<0.001.