Research Paper Volume 12, Issue 16 pp 16099—16110

Figure 1. Increased expression of IL-21 in UC patients. (A) The expression of IL-21 in colonic mucosa from UC patients and healthy volunteers. n=15. (B) The protein level of IL-21in human samples. n=5. (C) Representative images of immunohistochemistry staining with IL-21. (D) Changes in body weight in different groups of mice. n=10. (E) The protein level of IL-21 in different groups. n=10. (F) The mRNA level of IL1β, IL6, and TNFα in plasma. n=5. (G) The length of the colon in different groups of mice. (H) MPO activity detection in different groups of mice.n=5. (I) Serum FITC- dextran was used as a monitoring index of intestinal permeability. n=6. (J) The protein level of NF-κB/MAPKs/JNK signaling pathway components in different groups. n=5 *P < 0.05, **P < 0.01.