The cover features Figure 2 "TERRA expression in murine oocytes, early cleavage and blastocyst stage with regards to maternal age“ from Kordowitzki et al.
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Varela-Eirín M, Carpintero-Fernández P, Sánchez-Temprano A, Varela-Vázquez A, Paíno CL, Casado-Díaz A, Continente AC, Mato V, Fonseca E, Kandouz M, Blanco A, Caeiro JR, Mayán MD, . Senolytic activity of small molecular polyphenols from olive restores chondrocyte redifferentiation and promotes a pro-regenerative environment in osteoarthritis. . 12:15882-15905. https://doi.org/10.18632/aging.103801
Kordowitzki P, López de Silanes I, Guío-Carrión A, Blasco MA, . Dynamics of telomeric repeat-containing RNA expression in early embryonic cleavage stages with regards to maternal age. . 12:15906-15917. https://doi.org/10.18632/aging.103922
Luo L, Xu M, Du M, Kou H, Liao D, Cheng Z, Mei H, Hu Y, . Early coagulation tests predict risk stratification and prognosis of COVID-19. . 12:15918-15937. https://doi.org/10.18632/aging.103581
Li C, Chen Q, Wang J, Lin H, Lin Y, Lin J, Peng F, Chen J, Yang Z, . Clinical characteristics of chronic liver disease with coronavirus disease 2019 (COVID-19): a cohort study in Wuhan, China. . 12:15938-15945. https://doi.org/10.18632/aging.103632
Liu Y, Liu L, Wang Y, Du X, Ma H, Yao J, . Clinical course and characteristics of patients with coronavirus disease 2019 in Wuhan, China: a single-centered, retrospective, observational study. . 12:15946-15953. https://doi.org/10.18632/aging.103745
Chatterjee S, Sengupta T, Majumder S, Majumder R, . COVID-19: a probable role of the anticoagulant Protein S in managing COVID-19-associated coagulopathy. . 12:15954-15961. https://doi.org/10.18632/aging.103869
Lessi F, Grandi N, Mazzanti CM, Civita P, Scatena C, Aretini P, Bandiera P, Fornaciari A, Giuffra V, Fornaciari G, Naccarato AG, Tramontano E, Bevilacqua G, . A human MMTV-like betaretrovirus linked to breast cancer has been present in humans at least since the copper age. . 12:15978-15994. https://doi.org/10.18632/aging.103780
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Cecarini V, Bonfili L, Gogoi O, Lawrence S, Venanzi FM, Azevedo V, Mancha-Agresti P, Drumond MM, Rossi G, Berardi S, Galosi L, Cuccioloni M, Angeletti M, et al, . Neuroprotective effects of p62(SQSTM1)-engineered lactic acid bacteria in Alzheimer’s disease: a pre-clinical study. . 12:15995-16020. https://doi.org/10.18632/aging.103900
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Wang M, Guo J, Zhao Y, Wang J, . IL-21 mediates microRNA-423-5p /claudin-5 signal pathway and intestinal barrier function in inflammatory bowel disease. . 12:16099-16110. https://doi.org/10.18632/aging.103566
Chen Y, Zhou H, Chen F, Liu Y, Han L, Song M, Wang Z, Zhang W, Shang Y, Zhong M, . Testosterone ameliorates vascular aging via the Gas6/Axl signaling pathway. . 12:16111-16125. https://doi.org/10.18632/aging.103584
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Liu Y, Ma L, Shangguan F, Zhao X, Wang W, Gao Z, Zhou H, Qu G, Huang Y, An J, Xue J, Yang S, Cao Q, . LAIR-1 suppresses cell growth of ovarian cancer cell via the PI3K-AKT-mTOR pathway. . 12:16142-16154. https://doi.org/10.18632/aging.103589
Li G, Zhai Y, Liu H, Wang Z, Huang R, Jiang H, Feng Y, Chang Y, Wu F, Zeng F, Jiang T, Zhang W, . RPP30, a transcriptional regulator, is a potential pathogenic factor in glioblastoma. . 12:16155-16171. https://doi.org/10.18632/aging.103596
Duan L, Lu Y, Xie W, Nong L, Jia Y, Tan A, Liu Y, . Leptin promotes bone metastasis of breast cancer by activating the SDF-1/CXCR4 axis. . 12:16172-16182. https://doi.org/10.18632/aging.103599
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Seiler A, Schöngrundner S, Stock B, Nöth U, Hattingen E, Steinmetz H, Klein JC, Baudrexel S, Wagner M, Deichmann R, Gracien R, . Cortical aging – new insights with multiparametric quantitative MRI. . 12:16195-16210. https://doi.org/10.18632/aging.103629
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Lai Q, Li Q, He C, Fang Y, Lin S, Cai J, Ding J, Zhong Q, Zhang Y, Wu C, Wang X, He J, Liu Y, et al, . CTCF promotes colorectal cancer cell proliferation and chemotherapy resistance to 5-FU via the P53-Hedgehog axis. . 12:16270-16293. https://doi.org/10.18632/aging.103648
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Sumida K, Han Z, Dashputre AA, Potukuchi PK, Kovesdy CP, . Association between Nrf2 and CDKN2A expression in patients with end-stage renal disease: a pilot study. . 12:16357-16367. https://doi.org/10.18632/aging.103685
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Breen M, Nwanaji-Enwerem JC, Karrasch S, Flexeder C, Schulz H, Waldenberger M, Kunze S, Ollert M, Weidinger S, Colicino E, Gao X, Wang C, Shen J, et al, . Accelerated epigenetic aging as a risk factor for chronic obstructive pulmonary disease and decreased lung function in two prospective cohort studies. . 12:16539-16554. https://doi.org/10.18632/aging.103784
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Lin J, Kuo W, Baskaran R, Kuo C, Chen Y, Chen WS, Ho T, Day CH, Mahalakshmi B, Huang C, . Correction for: Swimming exercise stimulates IGF1/PI3K/Akt and AMPK/SIRT1/PGC1α survival signaling to suppress apoptosis and inflammation in aging hippocampus. . 12:16663-16664. https://doi.org/10.18632/aging.104045