Research Paper Volume 12, Issue 16 pp 16099—16110

Figure 5. The effect of miR-423-5p in DSS mice. (A) Changes in body weight in different groups of mice. n=10. (B) The mRNA level of IL1β, IL6, and TNFα in plasma. n=5. (C) The length of the colon in different groups of mice. (D) MPO activity detection in different groups of mice. n=4. (E) Serum FITC- dextran was used as a monitoring index of intestinal permeability. n=5. (F) Representative images of H&E staining. (G) The expression of claudin-5 in different groups. n=4. (H) Representative images of immunofluorescence staining with claudin-5. (I) The protein level of NF-κB/MAPKs/JNK signaling pathway components in different groups. n=5. *P < 0.05, **P < 0.01.