Research Paper Volume 12, Issue 17 pp 16852—16866
Spermidine inhibits neurodegeneration and delays aging via the PINK1-PDR1-dependent mitophagy pathway in C. elegans
Figure 2. Effect of spermidine on NL5901 worms. (A) Effect of different concentrations of spermidine treatment on survival curves of NL5901 worms, n=79-100. (B) Effect of 5mM spermidine treatment on the level of α-synuclein of NL5901 worms, n=14-18. (C) Effect of 5mM spermidine treatment on locomotor capacity of N2 and NL5901 worms, n=20. (D) Effect of 5mM spermidine treatment on chemotaxis memory of NL5901 worms, n=3. (E) Effect of 5mM spermidine treatment on autophagy-related genes bec-1 and sqst-1 of NL5901 worms, n=3. Data are represented as mean± SD, *P < 0.05, **P < 0.01 vs control.