Research Paper Volume 12, Issue 17 pp 16852—16866
Spermidine inhibits neurodegeneration and delays aging via the PINK1-PDR1-dependent mitophagy pathway in C. elegans
Figure 3. Effect of spermidine on UM0001 worms. (A) Effect of different concentrations of spermidine treatment on survival curves of UM0001 worms, n=81-98. (B) Effect of 5mM spermidine treatment on lipofuscin deposition level of UM0001 worms, n=12-15. (C) Effect of 5mM spermidine treatment on locomotor capacity of N2 and UM0001 worms, n=20. (D) Effect of 5mM spermidine treatment on chemotaxis memory of UM0001 worms, n=3. (E) Effect of 5mM spermidine treatment on autophagy-related genes bec-1 and sqst-1 of UM0001 worms, n=3. Data are represented as mean± SD, *P < 0.05, **P < 0.01 vs control.