Research Paper Volume 12, Issue 17 pp 16899—16920
Umbilical cord mesenchymal stem cells protect thymus structure and function in aged C57 mice by downregulating aging-related genes and upregulating autophagy- and anti-oxidative stress-related genes
Figure 16. SOD expression level in the mouse thymus after treatment with mUCMSCs. Note: (A, B) show immunohistochemical staining of SOD in thymus tissue after treatment for 1 month in the treatment group. The levels of SOD1 were increased to different degrees in the treatment group. (C, D) show immunohistochemical staining of SOD in the mouse thymus tissue of the model control group. (E, F) show immunohistochemical staining of thymus SOD in young control mice. (G) shows the difference in SOD expression in mouse thymus tissue between different groups after mUCMSC treatment. All dark brown tissue sections were strongly positive, brownish-yellow staining was moderately positive, light yellow staining was weakly positive, and blue nuclei were negative. *** indicates p < 0.001, ** indicates p < 0.01, * indicates p < 0.05, and NS indicates p > 0.05.