Research Paper Volume 12, Issue 17 pp 16899—16920
Umbilical cord mesenchymal stem cells protect thymus structure and function in aged C57 mice by downregulating aging-related genes and upregulating autophagy- and anti-oxidative stress-related genes
Figure 19. Expression of LC3 in the mouse thymus after treatment with mUCMSCs. Note: (A, B) show LC3 immunohistochemical staining of the thymus tissue after treatment in the treatment group. The levels of LC3 were increased to different degrees in the treatment group. (C, D) show LC3 immunohistochemical staining of the mouse thymus tissue in the model control group. (E, F) show immunohistochemical staining of thymus LC3 in young control mice. (G) Shows the difference in Lc3 expression in mouse thymus tissue between different groups after treatment with mUCMSCs. All dark brown tissue sections were strongly positive, brownish-yellow staining was moderately positive, light yellow staining was weakly positive, and blue nuclei were negative. *** indicates p < 0.001, ** indicates p < 0.01, * indicates p < 0.05, and NS indicates p > 0.05.