Research Paper Volume 12, Issue 16 pp 16155—16171

RPP30, a transcriptional regulator, is a potential pathogenic factor in glioblastoma

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Figure 5. Expression pattern and pathways associated with RPP30 expression in primary GBM of CGGA and TCGA databases. (A) The heatmap showed the expression pattern of RPP30 and transcription-related genes in GBM. Transcription-related genes were obtained from the AmiGO 2 Web portals. Besides, there was no difference in RPP30 expression between different genders of GBM. (B) The scatter plot showed the pathways closely related to RPP30 in CGGA and TCGA databases. There were 8 pathways positively and 8 pathways negatively correlated with RPP30 expression in both CGGA and TCGA databases. (C) The correlation coefficient and p-value of the above 16 pathways with RPP30 were shown in the table. The statistical significance was assessed by Pearson correlation analysis.