Research Paper Volume 12, Issue 18 pp 18084—18098

RAI14 silencing suppresses progression of esophageal cancer via the STAT3 pathway

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Figure 5. RAI14 regulates the STAT3 pathway and related factors. (A) The GSEA showed that the level of RAI14 level was positively correlated with STAT3-activated gene signatures (DAUER_STAT3_TARGETS_UP). (B) Western blotting of RAI14, p-STAT3, total STAT3, Mcl-1, cyclin D1, and cleaved caspase-3 in RAI14-modulated cells. GAPDH was used as the control.