Research Paper Volume 12, Issue 17 pp 17022—17037

Retrospective study of gene signatures and prognostic value of m6A regulatory factor in non-small cell lung cancer using TCGA database and the verification of FTO

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Figure 5. Effects of silencing FTO on proliferation and mRNA m6A level of lung cancer cells. (A) The mRNA m6A level in human lung cancer cell. (B) The expression of FTO in lung cancer cells. (C) Verification of knockout efficiency. (D) Knockdown of proliferation capacity of FTO inhibited lung cancer cells. (*, p < 0.05; **, p < 0.01; ***, ****, p < 0.001).