Research Paper Volume 12, Issue 17 pp 17062—17078
Evidence that dysplasia related microRNAs in Barrett’s esophagus target PD-L1 expression and contribute to the development of esophageal adenocarcinoma
Figure 4. The expression of microRNA predicted to target programmed death ligand 1 (PD-L1) is lower in BE and EAC with PD-L1 positivity. TaqMan real-time RT-PCR to validate the expression levels of miR-15a, -15b, -16, and -193a-3p using the combined cohort of 25 BE and 48 EAC patients with PD-L1 positive samples compared to those PD-L1 negative patients (43 BE and 44 EAC). Healthy controls with positive PD-L1 patients (n=22) and negative PD-L1 patients (n=56) were also included for comparison. Data shown are as mean ± SD.