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Research Paper Volume 12, Issue 17 pp 17099—17113

Sirt6 is required for spermatogenesis in mice

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Figure 2. Sirt6 is not essential to meiosis during spermatogenesis. (A, B) Spermatocytes of Sirt6+/+ and Sirt6-/- stained with SYCP3 (green) and γH2AX (red) antibodies, 8-week mice, n=4; 200 cells were used for each group. (C, D) Spermatocytes of Sirt6+/+ and Sirt6-/- stained for SYCP3 (green) and SYCP1 (red), 8-week mice, n=4; 200 cells were used for each group.