Research Paper Volume 12, Issue 17 pp 17271—17287

Profiling of circular RNAs in age-related cataract reveals circZNF292 as an antioxidant by sponging miR-23b-3p

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Figure 2. Total circRNAs detected by RNA-seq in ARC and normal tissues. (A) Overlaps of circRNAs identified in this study (ARC and the normal group) and CircBase. (B) The number of circRNAs and junction reads identified in ARC and normal tissues. (C) The genomic location of circRNAs. (D) The length distribution of exonic circRNAs. (E) The hierarchical clustering of circRNAs differentially expressed in ARC and normal tissues. Each row corresponds to a circRNA, and each column corresponds to a sample. The expression value is represented by a color scale. Intensity increases from green (relatively low expression) to red (relatively high expression).