Research Paper Volume 12, Issue 16 pp 16437—16456

Figure 6. Downregulation of KCNN4 inhibited the migration and invasion of PTC cell lines. (A, B) Transwell migration and Matrigel invasion assays in the KCNN4-knockdown group and the corresponding control group in three PTC cell lines. The quantitative results of the migration and invasion assays were determined from five random fields. (C) A wound-healing assay indicated that downregulating KCNN4 reduced the migration abilities of PTC cell lines. The data came from at least two independent experiments. *p<0.05, **p<0.01, ***p<0.001, ****p<0.0001 in comparison with the Si-NC group using Student’s t-test.