Figure 5. GSEA analysis of BC grouped by CLIC2 expression. GSEA was performed on RNA-Seq profiles of 1,053 breast cancer grouped by CLIC2 expression (high CLIC2 expression, n = 526; low CLIC2 expression, n = 527), and the top-ranked signatures were showing. (A) cytokine-cytokine receptor interaction; (B) cell adhesion molecules CAMs; (C) chemokine signaling pathway; (D) hematopoietic cell lineage; (E) JAK-STAT signaling pathway; (F) leukocyte transendothelial migration. GSEA, gene set enrichment analysis.